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    CG3735 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37803, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3735provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034933
    Locus tag
    Dmel_CG3735
    See related
    AllianceGenome:FB:FBgn0034933
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3735; UTP25
    Summary
    Predicted to enable U3 snoRNA binding activity and rRNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in embryonic/larval hypodermal muscle cell. Orthologous to human UTP25 (UTP25 small subunit processome component). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3735 in Genome Data Viewer
    Location:
    60A12-60A12; 2-105 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23937077..23939754, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19824600..19827277, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44806 Neighboring gene kazachoc Neighboring gene uncharacterized protein Neighboring gene Sarco/endoplasmic reticulum Ca(2+)-ATPase Neighboring gene Transaldolase Neighboring gene G protein alpha subunit s

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. piggyBac-based insertional mutagenesis and enhancer detection as a tool for functional insect genomics. Horn C, et al. Genetics, 2003 Feb. PMID 12618403, Free PMC Article
    2. Extensive translation of small Open Reading Frames revealed by Poly-Ribo-Seq. Aspden JL, et al. Elife, 2014 Aug 21. PMID 25144939, Free PMC Article
    3. Regulation of Ribosome Biogenesis and Protein Synthesis Controls Germline Stem Cell Differentiation. Sanchez CG, et al. Cell Stem Cell, 2016 Feb 4. PMID 26669894, Free PMC Article
    4. Genetic modifiers of tauopathy in Drosophila. Shulman JM, et al. Genetics, 2003 Nov. PMID 14668378, Free PMC Article
    5. The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub. Kwong PN, et al. J Biol Chem, 2015 Dec 11. PMID 26483546, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables U3 snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables U3 snoRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3735-PA
    CG3735-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23937077..23939754 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299868.1 → NP_001286797.1  uncharacterized protein Dmel_CG3735, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286797.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9UNG3, Q9W1G1
      Conserved Domains (1) summary
      pfam06862
      Location:211 → 696
      UTP25; Utp25, U3 small nucleolar RNA-associated SSU processome protein 25

    2. NM_138007.3 → NP_611851.1  uncharacterized protein Dmel_CG3735, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611851.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A9UNG3, Q9W1G1
      Related
      FBpp0072119
      Conserved Domains (1) summary
      pfam06862
      Location:211 → 696
      UTP25; Utp25, U3 small nucleolar RNA-associated SSU processome protein 25
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q960T7 Q960T7
    Q9W1G1 Q9W1G1

    Gene LinkOut

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