Rim2 Replication in mitochondria 2 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Rim2provided by FlyBase
Official Full Name: Replication in mitochondria 2provided by FlyBase
Primary source: FLYBASE:FBgn0031359
Locus tag: Dmel_CG18317
See related: AllianceGenome:FB:FBgn0031359
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG18317; Dmel\CG18317; drim2
Summary: Predicted to enable pyrimidine nucleotide transmembrane transporter activity. Involved in several processes, including deoxynucleotide transport; mitochondrial transcription; and mitochondrion distribution. Located in mitochondrion. Is expressed in several structures, including adult head and larval imaginal tissue. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 8. Orthologous to several human genes including SLC25A36 (solute carrier family 25 member 36). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
NEW: Try the new Gene table
Try the new Transcript table

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (1716244..1724388, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (1716244..1724388, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Drosophila mitochondrial carrier dRIM2 transports all DNA precursors and is essential to maintain mitochondrial function
Title: Functional characterization of drim2, the Drosophila melanogaster homolog of the yeast mitochondrial deoxynucleotide transporter.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables pyrimidine nucleotide transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables pyrimidine nucleotide transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cellular respiration	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in deoxynucleotide transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in locomotion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrial genome maintenance	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrial transcription	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrion distribution	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in mitochondrion organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in pyrimidine nucleotide import into mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IDA Inferred from Direct Assay more info	PubMed

Names: CG18317-PA; CG18317-PC; CG18317-PD; Rim2 ortholog; Rim2-PA; Rim2-PC; Rim2-PD

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain