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    CG17752 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42337, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG17752provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038718
    Locus tag
    Dmel_CG17752
    See related
    AllianceGenome:FB:FBgn0038718
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG17752
    Summary
    Predicted to enable organic anion transmembrane transporter activity. Predicted to be involved in organic anion transport. Predicted to be located in plasma membrane. Is expressed in several structures, including adult head; anterior endoderm; embryonic/larval midgut primordium; germline cell; and somatic trunk mesoderm derivative. Human ortholog(s) of this gene implicated in Lynch syndrome and mismatch repair cancer syndrome. Orthologous to several human genes including SLC22A10 (solute carrier family 22 member 10); SLC22A11 (solute carrier family 22 member 11); and SLC22A12 (solute carrier family 22 member 12). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17752 in Genome Data Viewer
    Location:
    92A10-92A10; 3-66 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (19610225..19612437)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15435947..15438159)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mir-9373 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. Engelhart DC, et al. Int J Mol Sci, 2020 Mar 15. PMID 32183456, Free PMC Article
    2. Parallel Gene Expression Differences between Low and High Latitude Populations of Drosophila melanogaster and D. simulans. Zhao L, et al. PLoS Genet, 2015 May. PMID 25950438, Free PMC Article
    3. Using FlyAtlas to identify better Drosophila melanogaster models of human disease. Chintapalli VR, et al. Nat Genet, 2007 Jun. PMID 17534367
    4. Transcriptome response to heavy metal stress in Drosophila reveals a new zinc transporter that confers resistance to zinc. Yepiskoposyan H, et al. Nucleic Acids Res, 2006. PMID 16973896, Free PMC Article
    5. Xbp1 targets canonical UPR(ER) and non-canonical pathways in separate tissues to promote longevity. Li M, et al. iScience, 2024 Jun 21. PMID 38832022, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables organic anion transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in organic anion transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17752-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      19610225..19612437
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142560.2 → NP_650817.1  uncharacterized protein Dmel_CG17752 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650817.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VDV7
      Related
      FBpp0083193, FBtr0083779
      Conserved Domains (2) summary
      cd06174
      Location:116 → 488
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:11 → 498
      2A0119; cation transport protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VDV7 Q9VDV7

    Gene LinkOut

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