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    cutlet cutlet [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 44637, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cutletprovided by FlyBase
    Official Full Name
    cutletprovided by FlyBase
    Primary source
    FLYBASE:FBgn0015376
    Locus tag
    Dmel_CG33122
    See related
    AllianceGenome:FB:FBgn0015376
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10030; CG33122; chl12; Ctf18; ctl; Dmel\CG33122
    Summary
    Predicted to enable DNA binding activity. Predicted to contribute to DNA clamp loader activity. Located in nucleus. Is expressed in several structures, including antennal primordium; central brain primordium; embryonic central brain neurons; head epidermis primordium; and ventral ectoderm. Orthologous to human CHTF18 (chromosome transmission fidelity factor 18). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See cutlet in Genome Data Viewer
    Location:
    24C1-24C1; 2-11 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3707230..3711748, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3707230..3711748, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene lectin-24A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Division-independent differentiation mandates proliferative competition among stem cells. Reilein A, et al. Proc Natl Acad Sci U S A, 2018 Apr 3. PMID 29555768, Free PMC Article
    2. Genetic analysis of the foraging microregion of Drosophila melanogaster. de Belle JS, et al. Genome, 1993 Feb. PMID 8458574
    3. Structure-specific abnormalities associated with mutations in a DNA replication accessory factor in Drosophila. Jaffe AB, et al. Dev Biol, 2001 Feb 15. PMID 11161570
    4. Transcriptional regulation of the Drosophila rfc1 gene by the DRE-DREF pathway. Tsuchiya A, et al. FEBS J, 2007 Apr. PMID 17381512
    5. Opposing JAK-STAT and Wnt signaling gradients define a stem cell domain by regulating differentiation at two borders. Melamed D, et al. Elife, 2020 Nov 2. PMID 33135631, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to DNA clamp loader activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of Ctf18 RFC-like complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cutlet
    Names
    CG33122-PA
    cutlet-PA
    gilead

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3707230..3711748 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_175955.3 → NP_787969.1  cutlet [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_787969.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IQ05, Q95WV5
      UniProtKB/TrEMBL
      Q8T3K3
      Related
      FBpp0077230
      Conserved Domains (1) summary
      cd00009
      Location:424 → 555
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQ05.2 Q8IQ05
    Q8T3K3 Q8T3K3

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