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    CG12384 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36224, updated on 27-Dec-2024

    Summary

    Official Symbol
    CG12384provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033624
    Locus tag
    Dmel_CG12384
    See related
    AllianceGenome:FB:FBgn0033624
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH16986; BcDNA:RH17411; Dmel\CG12384
    Summary
    Predicted to enable death domain binding activity and ribosome binding activity. Predicted to be involved in apoptotic signaling pathway; cellular response to amino acid starvation; and negative regulation of metabolic process. Is expressed in several structures, including embryonic dorsal epidermis; embryonic epipharynx; embryonic hypopharynx; embryonic proventriculus inner layer; and gut section. Orthologous to human DAP (death associated protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG12384 in Genome Data Viewer
    Location:
    47F5-47F5; 2-64 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11357902..11359176, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7245407..7246681, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene iotaTrypsin Neighboring gene transfer RNA:Selenocysteine-TCA 1-1 Neighboring gene intersex Neighboring gene separation anxiety

    Genomic regions, transcripts, and products

    Interactions

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables death domain binding  
    enables ribosome binding  
    Process Evidence Code Pubs
    involved_in apoptotic process  
    involved_in apoptotic signaling pathway  
    involved_in cellular response to amino acid starvation  
    involved_in negative regulation of DNA-templated transcription  
    involved_in negative regulation of autophagy  
    involved_in ribosome hibernation  
    Component Evidence Code Pubs
    is_active_in cellular_component  

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG12384-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11357902..11359176 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136832.4 → NP_610676.2  uncharacterized protein Dmel_CG12384 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610676.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JRC0
      Related
      FBpp0087252
      Conserved Domains (1) summary
      pfam15228
      Location:10 → 96
      DAP; Death-associated protein
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