Rpn3 Regulatory particle non-ATPase 3 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Rpn3provided by FlyBase
Official Full Name: Regulatory particle non-ATPase 3provided by FlyBase
Primary source: FLYBASE:FBgn0261396
Locus tag: Dmel_CG42641
See related: AllianceGenome:FB:FBgn0261396
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG10484; CG42641; Dmel\CG42641; Dox; Dox-A2; DoxA2; DXA2_DROME; l(2)37Bf; l(2)37Bf[+]; p58; RPN3; S3
Old locus tag: Dmel_CG10484
Summary: Enables zinc ion binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Part of proteasome regulatory particle. Is expressed in adult head and adult heart. Orthologous to human PSMD3 (proteasome 26S subunit, non-ATPase 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (19051790..19053681)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (19051790..19053681)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables enzyme regulator activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IC Inferred by Curator more info	PubMed
involved_in regulation of protein catabolic process	IEA Inferred from Electronic Annotation more info
involved_in ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of proteasome complex	IDA Inferred from Direct Assay more info	PubMed
part_of proteasome complex	IEA Inferred from Electronic Annotation more info
part_of proteasome regulatory particle	IDA Inferred from Direct Assay more info	PubMed
part_of proteasome regulatory particle	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of proteasome regulatory particle, lid subcomplex	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome regulatory particle, lid subcomplex	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Names: 3; CG42641-PA; CG42641-PB; Rpn3-PA; Rpn3-PB; diphenol oxidase A2; diphenol oxidase-A2; regulatory particle nonATPase

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