U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Orcokinin orcokinin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37806, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Orcokininprovided by FlyBase
    Official Full Name
    orcokininprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034935
    Locus tag
    Dmel_CG13565
    See related
    AllianceGenome:FB:FBgn0034935
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH09340; CG13565; CG1565; Dmel\CG13565; OK; OK-A; OK-B; Orco; orcokinin
    Summary
    Involved in male courtship behavior and positive regulation of oogenesis. Is expressed in several structures, including accessory medulla; adult brain; adult ventral nerve cord cell body rind; extraembryonic structure; and gut section. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Orcokinin in Genome Data Viewer
    Location:
    60A13-60A13; 2-105 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23946959..23949076, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19834482..19836599, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Transaldolase Neighboring gene G protein alpha subunit s Neighboring gene Stomatin like 2 Neighboring gene fizzy-related 2 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Orcokinin neuropeptides regulate reproduction in the fruit fly, Drosophila melanogaster. Silva V, et al. Insect Biochem Mol Biol, 2021 Dec. PMID 34742859
    2. Isoform-specific expression of the neuropeptide orcokinin in Drosophila melanogaster. Chen J, et al. Peptides, 2015 Jun. PMID 25600008
    3. More Drosophila enteroendocrine peptides: Orcokinin B and the CCHamides 1 and 2. Veenstra JA, et al. Cell Tissue Res, 2014 Sep. PMID 24850274
    4. Spatiotemporal organization of enteroendocrine peptide expression in Drosophila. Jang S, et al. J Neurogenet, 2021 Sep-Dec. PMID 34670462
    5. Mastermind mutations generate a unique constellation of midline cells within the Drosophila CNS. Zhang Y, et al. PLoS One, 2011. PMID 22046261, Free PMC Article

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Specification of the Drosophila Orcokinin A neurons by combinatorial coding.
      Title: Specification of the Drosophila Orcokinin A neurons by combinatorial coding.
    2. orcokinin B, CCHamide 1, and CCHamide 2 expression in Drosophila is reported.
      Title: More Drosophila enteroendocrine peptides: Orcokinin B and the CCHamides 1 and 2.
    3. Orcokinin neuropeptides regulate reproduction in the fruit fly, Drosophila melanogaster.
      Title: Orcokinin neuropeptides regulate reproduction in the fruit fly, Drosophila melanogaster.
    4. Existence and differential expression of the two orcokinin isoforms in the Drosophila brain and gut.
      Title: Isoform-specific expression of the neuropeptide orcokinin in Drosophila melanogaster.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in male courtship behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of oogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    orcokinin
    Names
    CG13565-PA
    CG13565-PB
    CG13565-PC
    Drm orcokinin
    Orcokinin-PA
    Orcokinin-PB
    Orcokinin-PC
    orcokinin B

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23946959..23949076 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138008.4 → NP_611852.2  orcokinin, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611852.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W1F8
      Related
      FBpp0072118

    2. NM_001274231.2 → NP_001261160.1  orcokinin, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261160.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LHE6

    3. NM_001299870.1 → NP_001286799.1  orcokinin, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286799.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LHE6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LHE6 A0A0B4LHE6
    Q9W1F8 Q9W1F8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools