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    mus302 mutagen-sensitive 302 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39874, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mus302provided by FlyBase
    Official Full Name
    mutagen-sensitive 302provided by FlyBase
    Primary source
    FLYBASE:FBgn0287696
    Locus tag
    Dmel_CG13025
    See related
    AllianceGenome:FB:FBgn0287696
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13025; Dmel\CG13025; mus(3)302
    Summary
    Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Predicted to be involved in protein ubiquitination. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mus302 in Genome Data Viewer
    Location:
    73C4-73C4; 3-44 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16776531..16779736, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16769631..16772836, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46214 Neighboring gene Neurotactin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene eukaryotic translation initiation factor 3 subunit e

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Preliminary data suggesting that females of the repair-deficient strain designated st mus302 are strong potentiators of chromosome loss induced by procarbazine and diethylnitrosamine (DEN) in the male genome of Drosophila. Zimmering S. Mutat Res, 1982 Feb. PMID 6799806
    2. The Drosophila melanogaster Ortholog of RFWD3 Functions Independently of RAD51 During DNA Repair. Carvajal-Garcia J, et al. G3 (Bethesda), 2020 Mar 5. PMID 31900333, Free PMC Article
    3. High frequency of spontaneous Minute mutations detected in the F1 progeny of interstrain matings between a recombination-defective mei-9L1 and the y w m f/sc8(y+) Y BS; dp strain of Drosophila melanogaster. Miyamoto T. Mutat Res, 1990 Mar. PMID 2106623
    4. Genetic study on the effects of the repair-deficient mutant females mei-9a, mei-41D5, mus101D1, mus104D1 and mus302D1 of Drosophila on spontaneous and X-ray-induced chromosome loss in the paternal genome. Cooper SF, et al. Mutat Res, 1981 May. PMID 6795496
    5. Mutants partially defective in excision repair at five autosomal loci in Drosophila melanogaster. Boyd JB, et al. Chromosoma, 1981. PMID 6785044

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in interstrand cross-link repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    mutagen-sensitive 302
    Names
    CG13025-PA
    CG13025-PB
    mus302-PA
    mus302-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      16776531..16779736 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140662.4 → NP_648919.1  mutagen-sensitive 302, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648919.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VV99
      Related
      FBpp0075105
      Conserved Domains (4) summary
      COG2319
      Location:318 → 415
      WD40; WD40 repeat [General function prediction only]
      pfam13639
      Location:130 → 180
      zf-RING_2; Ring finger domain
      sd00039
      Location:339 → 375
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:293 → 445
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_001275042.1 → NP_001261971.1  mutagen-sensitive 302, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261971.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VV99
      Conserved Domains (4) summary
      COG2319
      Location:318 → 415
      WD40; WD40 repeat [General function prediction only]
      pfam13639
      Location:130 → 180
      zf-RING_2; Ring finger domain
      sd00039
      Location:339 → 375
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:293 → 445
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VV99 Q9VV99

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