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    CG31007 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 318553, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG31007provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051007
    Locus tag
    Dmel_CG31007
    See related
    AllianceGenome:FB:FBgn0051007
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG31007
    Summary
    Predicted to be involved in mitochondrion organization. Predicted to be located in mitochondrial intermembrane space. Predicted to be active in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in frontotemporal dementia and/or amyotrophic lateral sclerosis 2; isolated mitochondrial myopathy; and spinal muscular atrophy, Jokela type. Orthologous to human CHCHD10 (coiled-coil-helix-coiled-coil-helix domain containing 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31007 in Genome Data Viewer
    Location:
    100B1-100B1; 3-102 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30991700..30992457, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26817422..26818179, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine (serotonin) receptor 7 Neighboring gene long non-coding RNA:CR46116 Neighboring gene long non-coding RNA:CR46117 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    2. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    3. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
    4. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    5. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrion organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial intermembrane space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31007-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30991700..30992457 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170533.3 → NP_733412.2  uncharacterized protein Dmel_CG31007 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_733412.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V6F6, Q8IMH1
      Conserved Domains (1) summary
      pfam06747
      Location:139 → 173
      CHCH; CHCH domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V6F6 Q4V6F6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
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