U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Remo Remoulade [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 2768909, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Remoprovided by FlyBase
    Official Full Name
    Remouladeprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030466
    Locus tag
    Dmel_CG15744
    See related
    AllianceGenome:FB:FBgn0030466
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15744; CT35992; Dmel\CG15744; Q7KV24_DROME
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head. Orthologous to several human genes including ADGRA2 (adhesion G protein-coupled receptor A2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See Remo in Genome Data Viewer
    Location:
    11E9-11E9; 1-42 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13288051..13294433)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13182084..13188466)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Histone deacetylase 4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45018 Neighboring gene uncharacterized protein Neighboring gene Inositol 1,4,5-triphosphate kinase 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Drosophila adhesion GPCR Remoulade regulates axon growth, branching, and guidance by modulating Rac1 GTPase. Yang X, et al. J Genet Genomics, 2024 Apr. PMID 38049063
    2. The adhesion G-protein-coupled receptor mayo/CG11318 controls midgut development in Drosophila. Vieira Contreras F, et al. Cell Rep, 2024 Jan 23. PMID 38180839
    3. Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation. Scholz N, et al. Nature, 2023 Mar. PMID 36890234
    4. Kek-6: A truncated-Trk-like receptor for Drosophila neurotrophin 2 regulates structural synaptic plasticity. Ulian-Benitez S, et al. PLoS Genet, 2017 Aug. PMID 28846707, Free PMC Article
    5. Molecular Basis for Cephalic Mechanosensitivity of Drosophila Larvae. Zhang Z, et al. Neurosci Bull, 2020 Sep. PMID 32761438, Free PMC Article

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables G protein-coupled receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell surface receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    remoulade
    Names
    CG15744-PA
    Remo-PA

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      13288051..13294433
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132642.3 → NP_572870.2  remoulade [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572870.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KV24
      Conserved Domains (7) summary
      smart00082
      Location:166 → 216
      LRRCT; Leucine rich repeat C-terminal domain
      smart00410
      Location:229 → 344
      IG_like; Immunoglobulin like
      sd00031
      Location:109 → 133
      LRR_1; leucine-rich repeat [structural motif]
      pfam12799
      Location:107 → 147
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:107 → 168
      LRR_8; Leucine rich repeat
      cl02422
      Location:366 → 412
      HRM; Hormone receptor domain
      cl21561
      Location:768 → 975
      7tm_4; Olfactory receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KV24 Q7KV24

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools