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    CG4520 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41902, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4520provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038355
    Locus tag
    Dmel_CG4520
    See related
    AllianceGenome:FB:FBgn0038355
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4520
    Summary
    Predicted to enable protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial outer membrane. Predicted to be part of mitochondrial outer membrane translocase complex. Is expressed in adult head and organism. Orthologous to human TOMM40L (translocase of outer mitochondrial membrane 40 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4520 in Genome Data Viewer
    Location:
    89A3-89A3; 3-58 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (15744654..15746411)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11570376..11572133)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk. Lu Y, et al. Nat Commun, 2016 Feb 1. PMID 26833246, Free PMC Article
    2. Genome-Wide Association Study on Male Genital Shape and Size in Drosophila melanogaster. Takahara B, et al. PLoS One, 2015. PMID 26182199, Free PMC Article
    3. Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development. Zheng Y, et al. BMC Genomics, 2023 May 26. PMID 37237333, Free PMC Article
    4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    5. A protein interaction map of Drosophila melanogaster. Giot L, et al. Science, 2003 Dec 5. PMID 14605208

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein import into mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein import into mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial outer membrane translocase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4520-PA
    CG4520-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      15744654..15746411
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300411.1 → NP_001287340.1  uncharacterized protein Dmel_CG4520, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287340.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VF44
      Conserved Domains (1) summary
      cd07305
      Location:33 → 312
      Porin3_Tom40; Translocase of outer mitochondrial membrane 40 (Tom40)

    2. NM_142226.1 → NP_650483.1  uncharacterized protein Dmel_CG4520, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650483.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VF44
      Related
      FBpp0082621, FBtr0083167
      Conserved Domains (1) summary
      cd07305
      Location:33 → 312
      Porin3_Tom40; Translocase of outer mitochondrial membrane 40 (Tom40)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VF44 Q9VF44

    Gene LinkOut

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