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    BomS2 Bomanin Short 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 49802, updated on 9-Dec-2024

    Summary

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    Official Symbol
    BomS2provided by FlyBase
    Official Full Name
    Bomanin Short 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0025583
    Locus tag
    Dmel_CG18106
    See related
    AllianceGenome:FB:FBgn0025583
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.2; BcDNA:RH08291; Bom2; bomS2; CG18106; DIM 2; DIM-2; DIM2; Dmel\CG18106; Im2; IM2
    Summary
    Involved in defense response. Located in extracellular region. Is expressed in larval central nervous system. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See BomS2 in Genome Data Viewer
    Location:
    55C4-55C4; 2-85 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (18386602..18387030)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (14274107..14274535)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Bomanin Short 1 Neighboring gene Bomanin Short 4 Neighboring gene Bomanin Bicipital 2 Neighboring gene Bomanin Short 3 Neighboring gene Bomanin Tailed 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The genetic basis of variation in immune defense against Lysinibacillus fusiformis infection in Drosophila melanogaster. Smith BR, et al. PLoS Pathog, 2023 Aug. PMID 37549163, Free PMC Article
    2. Inhibition of NF-κB in astrocytes is sufficient to delay neurodegeneration induced by proteotoxicity in neurons. Li YX, et al. J Neuroinflammation, 2018 Sep 11. PMID 30205834, Free PMC Article
    3. LncRNA-CR11538 Decoys Dif/Dorsal to Reduce Antimicrobial Peptide Products for Restoring Drosophila Toll Immunity Homeostasis. Zhou H, et al. Int J Mol Sci, 2021 Sep 18. PMID 34576280, Free PMC Article
    4. A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium. Huang J, et al. Proc Natl Acad Sci U S A, 2023 Mar 21. PMID 36917667, Free PMC Article
    5. Specific calcineurin isoforms are involved in Drosophila toll immune signaling. Li YX, et al. J Immunol, 2015 Jan 1. PMID 25429067

    See all (104) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in defense response IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in defense response IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in defense response NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in response to bacterium HEP PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bomanin short 2
    Names
    BomS2-PA
    CG18106-PA
    Immune-induced molecule 2
    Immune-induced peptide 2 precursor
    bomanin 2
    bomanin S2
    immune induced molecule 2
    immune induced peptide 2
    immune molecule 2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      18386602..18387030
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166277.3 → NP_725776.1  bomanin short 2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_725776.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O77150, Q8MLI5, Q9V8F9
      Related
      FBpp0085845
      Conserved Domains (1) summary
      pfam08194
      Location:13 → 40
      DIM; DIM protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O77150.2 O77150

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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