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    Neb-cGP Neb-cGP [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50417, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Neb-cGPprovided by FlyBase
    Official Full Name
    Neb-cGPprovided by FlyBase
    Primary source
    FLYBASE:FBgn0083167
    Locus tag
    Dmel_CG15304
    See related
    AllianceGenome:FB:FBgn0083167
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE31692; BcDNA:RH45340; CG15304; Dmel\CG15304; pncr006:X
    Summary
    Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be part of proton-transporting ATP synthase complex, coupling factor F(o). Predicted to be active in mitochondrial inner membrane. Is expressed in several structures, including adult head; adult heart; embryonic/larval midgut primordium; epithelium; and gut section. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 6. Orthologous to human ATP5MK (ATP synthase membrane subunit k). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Neb-cGP in Genome Data Viewer
    Location:
    9C4-9C5; 1-31 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10460736..10461878)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10354769..10355911)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Odorant receptor 9a Neighboring gene no circadian temperature entrainment Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ecdysteroids, juvenile hormone and insect neuropeptides: Recent successes and remaining major challenges. De Loof A. Gen Comp Endocrinol, 2008 Jan 1. PMID 17716674
    2. Gonadotropins in insects: an overview. De Loof A, et al. Arch Insect Biochem Physiol, 2001 Jul. PMID 11418931
    3. Identification of putative noncoding polyadenylated transcripts in Drosophila melanogaster. Tupy JL, et al. Proc Natl Acad Sci U S A, 2005 Apr 12. PMID 15809421, Free PMC Article
    4. Direct Testing for Allele-Specific Expression Differences Between Conditions. León-Novelo L, et al. G3 (Bethesda), 2018 Feb 2. PMID 29167272, Free PMC Article
    5. Genome-wide analysis reveals an unexpected function for the Drosophila splicing factor U2AF50 in the nuclear export of intronless mRNAs. Blanchette M, et al. Mol Cell, 2004 Jun 18. PMID 15200955

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    contributes_to proton-transporting ATP synthase activity, rotational mechanism IC
    Inferred by Curator
    more info
    		  
    Process Evidence Code Pubs
    involved_in proton motive force-driven ATP synthesis IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IC
    Inferred by Curator
    more info
    		  
    part_of proton-transporting ATP synthase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of proton-transporting ATP synthase complex, coupling factor F(o) ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Neb-cGP
    Names
    CG15304-PA
    CG15304-PB
    Neb-cGP-PA
    Neb-cGP-PB
    putative noncoding RNA 006:X

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10460736..10461878
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272479.1 → NP_001259408.1  Neb-cGP, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259408.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2U8
      Conserved Domains (1) summary
      pfam14960
      Location:1 → 47
      ATP_synth_reg; ATP synthase regulation

    2. NM_144291.4 → NP_652548.1  Neb-cGP, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652548.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2U8
      Related
      FBpp0071384
      Conserved Domains (1) summary
      pfam14960
      Location:1 → 47
      ATP_synth_reg; ATP synthase regulation
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W2U8 Q9W2U8

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