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    CG31917 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 326171, updated on 4-Jan-2025

    Summary

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    Official Symbol
    CG31917provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031668
    Locus tag
    Dmel_CG31917
    See related
    AllianceGenome:FB:FBgn0031668
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE52596; CG14038; Dmel\CG31917; Dmp18; Dromel_CG31917_FBtr0079037_mORF
    Summary
    Predicted to enable nucleosome binding activity. Involved in chromatin remodeling. Located in cytoplasm; nucleus; and polytene chromosome. Is expressed in several structures, including anterior endoderm; anterior endoderm anlage; embryonic/larval midgut; embryonic/larval midgut primordium; and head mesoderm. Orthologous to human ZNHIT1 (zinc finger HIT-type containing 1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See CG31917 in Genome Data Viewer
    Location:
    25C1-25C1; 2-15 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5009931..5010834, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5009931..5010834, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Reticulon-like1 Neighboring gene Transcription factor B5 Neighboring gene Selenoprotein T Neighboring gene viking

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Dmp8-Dmp18 bicistron messenger RNA enables unusual translation during cellular stress. Bucio-Mendez A, et al. J Cell Biochem, 2019 Mar. PMID 30270456
    2. Physical and functional interactions between Drosophila homologue of Swc6/p18Hamlet subunit of the SWR1/SRCAP chromatin-remodeling complex with the DNA repair/transcription factor TFIIH. Herrera-Cruz M, et al. J Biol Chem, 2012 Sep 28. PMID 22865882, Free PMC Article
    3. Chromatin remodeler Dmp18 regulates apoptosis by controlling H2Av incorporation in Drosophila imaginal disc development. Feng Y, et al. PLoS Genet, 2022 Sep. PMID 36166470, Free PMC Article
    4. Exhaustive identification of conserved upstream open reading frames with potential translational regulatory functions from animal genomes. Takahashi H, et al. Sci Rep, 2020 Oct 1. PMID 33004976, Free PMC Article
    5. Comparative genomic analysis of novel conserved peptide upstream open reading frames in Drosophila melanogaster and other dipteran species. Hayden CA, et al. BMC Genomics, 2008 Feb 1. PMID 18237443, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The Dmp8-Dmp18 bicistron messenger RNA enables unusual translation during cellular stress.
      Title: The Dmp8-Dmp18 bicistron messenger RNA enables unusual translation during cellular stress.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables nucleosome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin remodeling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Swr1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in polytene chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31917-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5009931..5010834 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135051.5 → NP_608895.1  uncharacterized protein Dmel_CG31917 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608895.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VMV7
      Related
      FBpp0078673
      Conserved Domains (1) summary
      pfam04438
      Location:111 → 139
      zf-HIT; HIT zinc finger
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMV7 Q9VMV7

    Gene LinkOut

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