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    Spatc1l spermatogenesis and centriole associated 1 like [ Mus musculus (house mouse) ]

    Gene ID: 76573, updated on 27-Nov-2024

    Summary

    Official Symbol
    Spatc1lprovided by MGI
    Official Full Name
    spermatogenesis and centriole associated 1 likeprovided by MGI
    Primary source
    MGI:MGI:1923823
    See related
    Ensembl:ENSMUSG00000009115 AllianceGenome:MGI:1923823
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700022B01Rik; 1700027D21Rik
    Summary
    Enables protein kinase A regulatory subunit binding activity. Acts upstream of or within several processes, including actin polymerization or depolymerization; positive regulation of cAMP-dependent protein kinase activity; and positive regulation of cAMP/PKA signal transduction. Located in centrosome and sperm head-tail coupling apparatus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human SPATC1L (spermatogenesis and centriole associated 1 like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 108.1) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Spatc1l in Genome Data Viewer
    Location:
    10 C1; 10 39.2 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (76394180..76406035)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (76561993..76570201)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene ybeY metallopeptidase Neighboring gene STARR-seq mESC enhancer starr_27182 Neighboring gene minichromosome maintenance complex component 3 associated protein Neighboring gene STARR-positive B cell enhancer ABC_E6874 Neighboring gene RIKEN cDNA 4930483K19 gene Neighboring gene lanosterol synthase Neighboring gene predicted gene 15343 Neighboring gene formiminotransferase cyclodeaminase Neighboring gene collagen, type VI, alpha 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase A regulatory subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein kinase A regulatory subunit binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in sperm head-tail coupling apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in sperm head-tail coupling apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    speriolin-like protein
    Names
    spermatogenesis and centriole-associated protein 1-like protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359186.1NP_001346115.1  speriolin-like protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK006232, AK006410, BX636056
      Consensus CDS
      CCDS88029.1
      UniProtKB/TrEMBL
      D3Z7D4
      Related
      ENSMUSP00000101054.2, ENSMUST00000105414.2
      Conserved Domains (1) summary
      pfam15058
      Location:5155
      Speriolin_N; Speriolin N terminus
    2. NM_029661.1NP_083937.1  speriolin-like protein isoform 1

      See identical proteins and their annotated locations for NP_083937.1

      Status: VALIDATED

      Source sequence(s)
      AK006410
      Consensus CDS
      CCDS23949.1
      UniProtKB/Swiss-Prot
      B2RW50, Q9D9W0
      Related
      ENSMUSP00000009259.5, ENSMUST00000009259.5
      Conserved Domains (2) summary
      pfam15058
      Location:5155
      Speriolin_N; Speriolin N terminus
      pfam15059
      Location:197342
      Speriolin_C; Speriolin C-terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      76394180..76406035
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314142.3XP_017169631.1  speriolin-like protein isoform X2

      Conserved Domains (2) summary
      pfam15058
      Location:141
      Speriolin_N; Speriolin N-terminus
      pfam15059
      Location:83228
      Speriolin_C; Speriolin C-terminus
    2. XM_006514279.3XP_006514342.1  speriolin-like protein isoform X1

      Conserved Domains (2) summary
      pfam15058
      Location:389
      Speriolin_N; Speriolin N-terminus
      pfam15059
      Location:131276
      Speriolin_C; Speriolin C-terminus