U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Rbms1 RNA binding motif, single stranded interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 56878, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rbms1provided by MGI
    Official Full Name
    RNA binding motif, single stranded interacting protein 1provided by MGI
    Primary source
    MGI:MGI:1861774
    See related
    Ensembl:ENSMUSG00000026970 AllianceGenome:MGI:1861774
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    YC1; MSSP-1; MSSP-2; MSSP-3; 2600014B10Rik
    Summary
    Predicted to enable mRNA 3'-UTR binding activity; poly(A) binding activity; and poly(U) RNA binding activity. Predicted to be involved in DNA replication. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and sensory organ. Orthologous to human RBMS1 (RNA binding motif single stranded interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in lung adult (RPKM 26.0), ovary adult (RPKM 17.9) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Rbms1 in Genome Data Viewer
    Location:
    2 C1.2; 2 34.95 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (60580537..60794224, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (60750193..60963880, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S21 pseudogene Neighboring gene integrin beta 6 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:60555461-60555644 Neighboring gene STARR-seq mESC enhancer starr_04618 Neighboring gene predicted gene, 33436 Neighboring gene VISTA enhancer mm1564 Neighboring gene STARR-seq mESC enhancer starr_04621 Neighboring gene STARR-seq mESC enhancer starr_04622 Neighboring gene STARR-positive B cell enhancer ABC_E9002 Neighboring gene STARR-positive B cell enhancer ABC_E5923 Neighboring gene predicted gene, 50617 Neighboring gene predicted gene 13582 Neighboring gene predicted gene, 33647 Neighboring gene predicted gene, 39833

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (3)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables poly(A) binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables poly(U) RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    RNA-binding motif, single-stranded-interacting protein 1
    Names
    single-stranded DNA-binding protein MSSP-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001141931.1NP_001135403.1  RNA-binding motif, single-stranded-interacting protein 1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded protein (isoform 2) has a shorter C-terminus, compared to isoform 1.
      Source sequence(s)
      AA175245, AK145897, AK147109, AK161102
      UniProtKB/TrEMBL
      Q3UKR8, Q3V0L4
      Conserved Domains (2) summary
      cd12470
      Location:53138
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:139224
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2
    2. NM_001141932.1NP_001135404.1  RNA-binding motif, single-stranded-interacting protein 1 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AA175245, AK145897, AK161102
      Consensus CDS
      CCDS50590.1
      UniProtKB/TrEMBL
      E9PZ21, Q3TTX8
      Related
      ENSMUSP00000131306.2, ENSMUST00000164147.8
      Conserved Domains (2) summary
      cd12470
      Location:53138
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:139224
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2
    3. NM_020296.2NP_064692.2  RNA-binding motif, single-stranded-interacting protein 1 isoform 3

      See identical proteins and their annotated locations for NP_064692.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has a different 5' UTR and 5' coding region and lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded protein (isoform 3) has a distinct N-terminus and a shorter C-terminus, compared to isoform 1.
      Source sequence(s)
      AA175245, AK147109, AK161102, BC016501
      Consensus CDS
      CCDS50591.1
      UniProtKB/Swiss-Prot
      Q3UI25, Q3UXU2, Q6PEU6, Q6PHC2, Q91W59, Q9WTK4
      UniProtKB/TrEMBL
      Q3UKR8, Q3V0L4
      Related
      ENSMUSP00000028347.7, ENSMUST00000028347.13
      Conserved Domains (2) summary
      cd12470
      Location:55140
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:141226
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      60580537..60794224 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006499940.2XP_006500003.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X1

      UniProtKB/TrEMBL
      Q3TTX8
      Conserved Domains (2) summary
      cd12470
      Location:55140
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:141226
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2
    2. XM_030251908.1XP_030107768.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X6

      UniProtKB/TrEMBL
      Q3UKR8, Q3V0L4
      Conserved Domains (2) summary
      cd12470
      Location:55140
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:141226
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2
    3. XM_017319146.1XP_017174635.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X3

      UniProtKB/TrEMBL
      Q3TTX8
      Conserved Domains (2) summary
      cd12470
      Location:55140
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:141226
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2
    4. XM_030251910.1XP_030107770.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X8

      UniProtKB/TrEMBL
      Q3UKR8, Q3V0L4
      Conserved Domains (2) summary
      cd12470
      Location:35120
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:121206
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2
    5. XM_006499942.3XP_006500005.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X5

      UniProtKB/TrEMBL
      Q3TTX8
      Conserved Domains (2) summary
      cd12470
      Location:35120
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:121206
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2
    6. XM_030251909.2XP_030107769.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X7

      UniProtKB/TrEMBL
      Q3UKR8, Q3V0L4
      Conserved Domains (2) summary
      cd12470
      Location:53138
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:139224
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2
    7. XM_030251907.2XP_030107767.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X4

      UniProtKB/TrEMBL
      Q3TTX8
      Conserved Domains (2) summary
      cd12470
      Location:53138
      RRM1_MSSP1; RNA recognition motif 1 in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12474
      Location:139224
      RRM2_MSSP2; RNA recognition motif 2 found in vertebrate single-stranded DNA-binding protein MSSP-2
    8. XM_036162420.1XP_036018313.1  RNA-binding motif, single-stranded-interacting protein 1 isoform X2

      UniProtKB/TrEMBL
      Q3TTX8
      Conserved Domains (2) summary
      cd12470
      Location:45130
      RRM1_MSSP1; RNA recognition motif 1 (RRM1) found in vertebrate single-stranded DNA-binding protein MSSP-1
      cd12473
      Location:131215
      RRM2_MSSP1; RNA recognition motif 2 (RRM2) found in vertebrate single-stranded DNA-binding protein MSSP-1