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    Cd82 CD82 antigen [ Mus musculus (house mouse) ]

    Gene ID: 12521, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cd82provided by MGI
    Official Full Name
    CD82 antigenprovided by MGI
    Primary source
    MGI:MGI:104651
    See related
    Ensembl:ENSMUSG00000027215 AllianceGenome:MGI:104651
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C33; IA4; Kai1; Tspan27
    Summary
    Predicted to be located in phagocytic vesicle. Predicted to be active in plasma membrane. Is expressed in several structures, including choroid plexus; foregut; limb segment; meninges; and olfactory epithelium. Orthologous to human CD82 (CD82 molecule). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in large intestine adult (RPKM 142.7), duodenum adult (RPKM 91.2) and 22 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Cd82 in Genome Data Viewer
    Location:
    2 E1; 2 51.62 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (93249447..93293295, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (93419102..93462950, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 32745 Neighboring gene predicted gene 13807 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:93264860-93264969 Neighboring gene STARR-positive B cell enhancer ABC_E5946 Neighboring gene microRNA 7001 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:93299170-93299353 Neighboring gene STARR-positive B cell enhancer ABC_E2630 Neighboring gene STARR-positive B cell enhancer ABC_E4482 Neighboring gene predicted gene 10804 Neighboring gene predicted gene, 54115 Neighboring gene predicted gene, 33010

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in phagocytic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    CD82 antigen
    Names
    C33 antigen
    inducible membrane protein R2
    kangai 1 (suppression of tumorigenicity 6, prostate)
    metastasis suppressor Kangai-1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001136055.2NP_001129527.1  CD82 antigen

      See identical proteins and their annotated locations for NP_001129527.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
      Source sequence(s)
      AK135381, AL732483, BM215013
      Consensus CDS
      CCDS16454.1
      UniProtKB/Swiss-Prot
      P40237
      UniProtKB/TrEMBL
      Q3UII2
      Related
      ENSMUSP00000112158.3, ENSMUST00000116457.9
      Conserved Domains (1) summary
      cd03160
      Location:106228
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    2. NM_001271430.1NP_001258359.1  CD82 antigen

      See identical proteins and their annotated locations for NP_001258359.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
      Source sequence(s)
      AK135381, AK160907, AL732483, BM215013
      Consensus CDS
      CCDS16454.1
      UniProtKB/Swiss-Prot
      P40237
      UniProtKB/TrEMBL
      Q3UII2
      Related
      ENSMUSP00000097287.2, ENSMUST00000099696.8
      Conserved Domains (1) summary
      cd03160
      Location:106228
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    3. NM_001271431.1NP_001258360.1  CD82 antigen

      See identical proteins and their annotated locations for NP_001258360.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
      Source sequence(s)
      AL732483
      Consensus CDS
      CCDS16454.1
      UniProtKB/Swiss-Prot
      P40237
      UniProtKB/TrEMBL
      Q3UII2
      Conserved Domains (1) summary
      cd03160
      Location:106228
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    4. NM_001271432.1NP_001258361.1  CD82 antigen

      See identical proteins and their annotated locations for NP_001258361.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
      Source sequence(s)
      AL732483
      Consensus CDS
      CCDS16454.1
      UniProtKB/Swiss-Prot
      P40237
      UniProtKB/TrEMBL
      Q3UII2
      Conserved Domains (1) summary
      cd03160
      Location:106228
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    5. NM_001271461.1NP_001258390.1  CD82 antigen

      See identical proteins and their annotated locations for NP_001258390.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
      Source sequence(s)
      AL732483
      Consensus CDS
      CCDS16454.1
      UniProtKB/Swiss-Prot
      P40237
      UniProtKB/TrEMBL
      Q3UII2
      Conserved Domains (1) summary
      cd03160
      Location:106228
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    6. NM_001271462.1NP_001258391.1  CD82 antigen

      See identical proteins and their annotated locations for NP_001258391.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
      Source sequence(s)
      AL732483
      Consensus CDS
      CCDS16454.1
      UniProtKB/Swiss-Prot
      P40237
      UniProtKB/TrEMBL
      Q3UII2
      Related
      ENSMUSP00000106888.2, ENSMUST00000111257.8
      Conserved Domains (1) summary
      cd03160
      Location:106228
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
    7. NM_007656.5NP_031682.1  CD82 antigen

      See identical proteins and their annotated locations for NP_031682.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the predominant transcript. Variants 1, 2, 3, 4, 5, 6 and 7 encode the same protein.
      Source sequence(s)
      AL732483
      Consensus CDS
      CCDS16454.1
      UniProtKB/Swiss-Prot
      P40237
      UniProtKB/TrEMBL
      Q3UII2
      Related
      ENSMUSP00000028644.5, ENSMUST00000028644.11
      Conserved Domains (1) summary
      cd03160
      Location:106228
      CD37_CD82_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD37_CD82_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      93249447..93293295 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)