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    Zg16 zymogen granule protein 16 [ Mus musculus (house mouse) ]

    Gene ID: 69036, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zg16provided by MGI
    Official Full Name
    zymogen granule protein 16provided by MGI
    Primary source
    MGI:MGI:1916286
    See related
    Ensembl:ENSMUSG00000049350 AllianceGenome:MGI:1916286
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ZG16p; 1810010M01Rik
    Summary
    Enables peptidoglycan binding activity. Acts upstream of or within defense response to Gram-positive bacterium and suppression of symbiont entry into host. Located in mucus layer. Orthologous to human ZG16 (zymogen granule protein 16). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in large intestine adult (RPKM 2660.4), small intestine adult (RPKM 1563.8) and 3 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Zg16 in Genome Data Viewer
    Location:
    7 F3; 7 69.3 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (126649328..126651847, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127050156..127052675, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134167876-134168063 Neighboring gene predicted gene, 53372 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134170996-134171192 Neighboring gene STARR-seq mESC enhancer starr_20164 Neighboring gene MYC-associated zinc finger protein (purine-binding transcription factor) Neighboring gene kinesin family member 22 Neighboring gene STARR-positive B cell enhancer ABC_E9708 Neighboring gene STARR-positive B cell enhancer ABC_E8210 Neighboring gene predicted gene, 22747 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:134234662-134234982 Neighboring gene expressed sequence AI467606

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (1)  1 citation

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidoglycan binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi lumen ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi lumen ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in collagen-containing extracellular matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in collagen-containing extracellular matrix ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mucus layer IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in zymogen granule membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in zymogen granule membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    zymogen granule membrane protein 16
    Names
    secretory lectin ZG16

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026918.3NP_081194.1  zymogen granule membrane protein 16 precursor

      See identical proteins and their annotated locations for NP_081194.1

      Status: VALIDATED

      Source sequence(s)
      AC122863
      Consensus CDS
      CCDS21856.1
      UniProtKB/Swiss-Prot
      Q8K0C5
      Related
      ENSMUSP00000145876.2, ENSMUST00000205424.2
      Conserved Domains (1) summary
      cd09611
      Location:31158
      Jacalin_ZG16_like; Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      126649328..126651847 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)