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    Adrm1 adhesion regulating molecule 1 26S proteasome ubiquitin receptor [ Mus musculus (house mouse) ]

    Gene ID: 56436, updated on 9-Dec-2024

    Summary

    Official Symbol
    Adrm1provided by MGI
    Official Full Name
    adhesion regulating molecule 1 26S proteasome ubiquitin receptorprovided by MGI
    Primary source
    MGI:MGI:1929289
    See related
    Ensembl:ENSMUSG00000039041 AllianceGenome:MGI:1929289
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Arm1; ARM-1; Gp110; Rpn13; 1110063P18Rik; 2510006J17Rik
    Summary
    Predicted to enable several functions, including endopeptidase activator activity; protease binding activity; and proteasome binding activity. Involved in several processes, including germ cell development; gonad development; and positive regulation of growth hormone receptor signaling pathway. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of proteasome regulatory particle, lid subcomplex. Is expressed in several structures, including genitourinary system; liver; sensory organ; and skeleton. Orthologous to human ADRM1 (ADRM1 26S proteasome ubiquitin receptor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 108.3), duodenum adult (RPKM 65.5) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Adrm1 in Genome Data Viewer
    Location:
    2 H4; 2 102.69 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (179813381..179818076)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (180171588..180176283)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 46782 Neighboring gene STARR-positive B cell enhancer ABC_E332 Neighboring gene oxysterol binding protein-like 2 Neighboring gene predicted gene, 29886 Neighboring gene STARR-positive B cell enhancer mm9_chr2:179905789-179906089 Neighboring gene microRNA 7005 Neighboring gene laminin, alpha 5 Neighboring gene STARR-seq mESC enhancer starr_06728 Neighboring gene STARR-seq mESC enhancer starr_06729 Neighboring gene STARR-positive B cell enhancer ABC_E6036 Neighboring gene microRNA 3091 Neighboring gene ribosomal protein S21

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Gene trapped (1) 
    • Targeted (3)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables endopeptidase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables endopeptidase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular function inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protease binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables proteasome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables proteasome binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of proteasome complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome regulatory particle, lid subcomplex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    proteasomal ubiquitin receptor ADRM1
    Names
    110 kDa cell membrane glycoprotein
    adhesion-regulating molecule 1
    glycoprotein 110
    rpn13 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019822.3NP_062796.2  proteasomal ubiquitin receptor ADRM1

      See identical proteins and their annotated locations for NP_062796.2

      Status: PROVISIONAL

      Source sequence(s)
      AL663027
      Consensus CDS
      CCDS17171.1
      UniProtKB/Swiss-Prot
      Q3UKZ8, Q8BPH8, Q922A7, Q9JKV1
      UniProtKB/TrEMBL
      A0A0A6YVU8
      Related
      ENSMUSP00000050076.5, ENSMUST00000061437.5
      Conserved Domains (2) summary
      cd13314
      Location:24128
      PH_Rpn13; Pleckstrin homology-like domain of Regulatory Particle Non-ATPase 13
      pfam16550
      Location:274381
      RPN13_C; UCH-binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      179813381..179818076
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)