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    Commd10 COMM domain containing 10 [ Mus musculus (house mouse) ]

    Gene ID: 69456, updated on 3-Dec-2024

    Summary

    Official Symbol
    Commd10provided by MGI
    Official Full Name
    COMM domain containing 10provided by MGI
    Primary source
    MGI:MGI:1916706
    See related
    Ensembl:ENSMUSG00000042705 AllianceGenome:MGI:1916706
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DRWMS2; VavCre; Vav-cre; Vav-iCre; Vav1-Cre; 2310003A05Rik; Tg(Vav1-icre)A2Kio
    Summary
    Predicted to be located in nucleoplasm. Orthologous to human COMMD10 (COMM domain containing 10). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 9.6), CNS E11.5 (RPKM 9.1) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Commd10 in Genome Data Viewer
    Location:
    18 C; 18 24.9 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (47091917..47242435)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (46958819..47087995)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene 3744 Neighboring gene STARR-positive B cell enhancer ABC_E5655 Neighboring gene predicted gene, 49974 Neighboring gene predicted gene, 22791 Neighboring gene STARR-positive B cell enhancer mm9_chr18:47157285-47157586 Neighboring gene STARR-seq mESC enhancer starr_44533 Neighboring gene heat shock protein 1 (chaperonin 10), related sequence 1 Neighboring gene ADP-ribosylation factor interacting protein 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    COMM domain-containing protein 10
    Names
    Tg(Vav1-cre)1Kio
    Tg(Vav1-cre)A2Kio
    down-regulated in W/WV mouse stomach 2
    mDRWMS2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418791.1NP_001405720.1  COMM domain-containing protein 10 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
    2. NM_001418792.1NP_001405721.1  COMM domain-containing protein 10 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
    3. NM_001418808.1NP_001405737.1  COMM domain-containing protein 10 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
      UniProtKB/TrEMBL
      A0A3Q4EHW7, Q3UTM6
      Related
      ENSMUSP00000157148.2, ENSMUST00000234961.2
    4. NM_001418809.1NP_001405738.1  COMM domain-containing protein 10 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC132100
      UniProtKB/TrEMBL
      Q3UTM6
      Related
      ENSMUSP00000157292.2, ENSMUST00000234124.2
    5. NM_001418810.1NP_001405739.1  COMM domain-containing protein 10 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
      UniProtKB/TrEMBL
      A0A3Q4EC50
      Related
      ENSMUSP00000157272.2, ENSMUST00000234701.2
    6. NM_001418811.1NP_001405740.1  COMM domain-containing protein 10 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
    7. NM_001418812.1NP_001405741.1  COMM domain-containing protein 10 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
    8. NM_001418813.1NP_001405742.1  COMM domain-containing protein 10 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
      UniProtKB/TrEMBL
      A0A3Q4EII3
      Related
      ENSMUSP00000157358.2, ENSMUST00000234280.2
    9. NM_001418814.1NP_001405743.1  COMM domain-containing protein 10 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
    10. NM_001418815.1NP_001405744.1  COMM domain-containing protein 10 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
      UniProtKB/TrEMBL
      A0A3Q4EGT0
      Related
      ENSMUSP00000157146.2, ENSMUST00000234085.2
    11. NM_001418816.1NP_001405745.1  COMM domain-containing protein 10 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
    12. NM_001418817.1NP_001405746.1  COMM domain-containing protein 10 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
    13. NM_178377.5NP_848464.1  COMM domain-containing protein 10 isoform 1

      See identical proteins and their annotated locations for NP_848464.1

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100
      Consensus CDS
      CCDS29238.1
      UniProtKB/Swiss-Prot
      Q8JZY2
      UniProtKB/TrEMBL
      Q3TKN7, Q3UTM6
      Related
      ENSMUSP00000041650.8, ENSMUST00000049388.9
      Conserved Domains (1) summary
      cd04758
      Location:15201
      Commd10; COMM_Domain containing protein 10. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several ...

    RNA

    1. NR_184828.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC117239, AC132100

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      47091917..47242435
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)