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    CG14483 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36995, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14483provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034248
    Locus tag
    Dmel_CG14483
    See related
    AllianceGenome:FB:FBgn0034248
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14483
    Summary
    Predicted to enable unfolded protein binding activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane. Is expressed in embryonic/larval midgut and organism. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 12. Orthologous to human PET100 (PET100 cytochrome c oxidase chaperone). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14483 in Genome Data Viewer
    Location:
    54C10-54C11; 2-83 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17585195..17586294, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13472700..13473799, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45274 Neighboring gene antisense RNA:CR45275 Neighboring gene Rho GTPase activating protein at 54D Neighboring gene icln Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Antagonistic pleiotropy for life-history traits at the gene expression level. Bochdanovits Z, et al. Proc Biol Sci, 2004 Feb 7. PMID 15101424, Free PMC Article
    2. The nonspecific lethal complex is a transcriptional regulator in Drosophila. Raja SJ, et al. Mol Cell, 2010 Jun 25. PMID 20620954
    3. Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. Li H, et al. DNA Res, 2016 Dec. PMID 27559081, Free PMC Article
    4. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article
    5. Comprehensive Identification and Alternative Splicing of Microexons in Drosophila. Pang TL, et al. Front Genet, 2021. PMID 33859668, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial cytochrome c oxidase assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14483-PA
    CG14483-PB
    CG14483-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17585195..17586294 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299612.1 → NP_001286541.1  uncharacterized protein Dmel_CG14483, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286541.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QPR8
      Conserved Domains (1) summary
      pfam09803
      Location:1 → 63
      Pet100

    2. NM_001274130.2 → NP_001261059.1  uncharacterized protein Dmel_CG14483, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261059.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QPR8
      Conserved Domains (1) summary
      pfam09803
      Location:1 → 63
      Pet100

    3. NM_137391.4 → NP_611235.1  uncharacterized protein Dmel_CG14483, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611235.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4QPR8
      Related
      FBpp0086059
      Conserved Domains (1) summary
      pfam09803
      Location:1 → 63
      Pet100
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4QPR8 Q4QPR8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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