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    YIP4 Yip4p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852676, updated on 9-Dec-2024

    Summary

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    Official Symbol
    YIP4
    Official Full Name
    Yip4p
    Primary source
    SGD:S000003166
    Locus tag
    YGL198W
    See related
    AllianceGenome:SGD:S000003166; FungiDB:YGL198W; VEuPathDB:YGL198W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables small GTPase binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi apparatus. Orthologous to human YIPF6 (Yip1 domain family member 6). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See YIP4 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (123591..124298)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene tRNA-Lys Neighboring gene Emp24p Neighboring gene Mds3p Neighboring gene D-serine ammonia-lyase DSD1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of Saccharomyces cerevisiae Genes Whose Deletion Causes Synthetic Effects in Cells with Reduced Levels of the Nuclear Pif1 DNA Helicase. Stundon JL, et al. G3 (Bethesda), 2015 Oct 19. PMID 26483010, Free PMC Article
    2. Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors. Calero M, et al. FEBS Lett, 2002 Mar 27. PMID 11943201
    3. Intrinsic tethering activity of endosomal Rab proteins. Lo SY, et al. Nat Struct Mol Biol, 2011 Dec 11. PMID 22157956, Free PMC Article
    4. Predicting protein functions from redundancies in large-scale protein interaction networks. Samanta MP, et al. Proc Natl Acad Sci U S A, 2003 Oct 28. PMID 14566057, Free PMC Article
    5. The phox homology (PX) domain protein interaction network in yeast. Vollert CS, et al. Mol Cell Proteomics, 2004 Nov. PMID 15263065

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables small GTPase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Yip4p
    NP_011317.2
    • Protein that interacts with Rab GTPases; localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      123591..124298
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181063.1 → NP_011317.2  TPA: Yip4p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011317.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTV5, P53093
      UniProtKB/TrEMBL
      A6ZTZ0, B3LHP7, C7GWZ6, C8Z855, G2WDQ8, N1P4J7
      Conserved Domains (1) summary
      cl21557
      Location:1 → 231
      Yip1; Yip1 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53093.2

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