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    BAP3 amino acid transporter BAP3 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851616, updated on 9-Dec-2024

    Summary

    Official Symbol
    BAP3
    Official Full Name
    amino acid transporter BAP3
    Primary source
    SGD:S000002453
    Locus tag
    YDR046C
    See related
    AllianceGenome:SGD:S000002453; FungiDB:YDR046C; VEuPathDB:YDR046C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    PAP1
    Summary
    Enables amino acid transmembrane transporter activity. Involved in amino acid transport and transmembrane transport. Located in endoplasmic reticulum and mitochondrion. Human ortholog(s) of this gene implicated in retinitis pigmentosa 68. Orthologous to several human genes including SLC7A1 (solute carrier family 7 member 1); SLC7A14 (solute carrier family 7 member 14); and SLC7A2 (solute carrier family 7 member 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See BAP3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (548762..550576, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene coproporphyrinogen oxidase Neighboring gene DNA-directed RNA polymerase III core subunit RPC11 Neighboring gene uroporphyrinogen decarboxylase HEM12 Neighboring gene Vms1p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables amino acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in amino acid transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in amino acid transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 

    General protein information

    Preferred Names
    amino acid transporter BAP3
    NP_010331.3
    • Amino acid permease; involved in uptake of cysteine, leucine, isoleucine and valine; BAP3 has a paralog, BAP2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      548762..550576 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180354.3NP_010331.3  TPA: amino acid transporter BAP3 [Saccharomyces cerevisiae S288C]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VS34, P41815
      UniProtKB/TrEMBL
      A6ZY13, B3LGM1, C7GTA3
      Conserved Domains (1) summary
      COG0833
      Location:40603
      LysP; Amino acid permease [Amino acid transport and metabolism]