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    CG30503 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246656, updated on 17-Dec-2024

    Summary

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    Official Symbol
    CG30503provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050503
    Locus tag
    Dmel_CG30503
    See related
    AllianceGenome:FB:FBgn0050503
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH50933; CG1672; Dmel\CG30503
    Summary
    Predicted to enable calcium-dependent phospholipase A2 activity. Predicted to be involved in arachidonate secretion and phospholipid metabolic process. Orthologous to human PLA2G3 (phospholipase A2 group III). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30503 in Genome Data Viewer
    Location:
    43C1-43C1; 2-56 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7443824..7445792, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3331329..3333297, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene sine oculis Neighboring gene long non-coding RNA:CR44204 Neighboring gene uncharacterized protein Neighboring gene kappaB-Ras Neighboring gene secretory Phospholipase A2 Neighboring gene uncharacterized protein Neighboring gene Fatty acid 2-hydroxylase Neighboring gene long non-coding RNA:CR45320

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Disruption of INOS, a Gene Encoding myo-Inositol Phosphate Synthase, Causes Male Sterility in Drosophila melanogaster. Jackson NAM, et al. G3 (Bethesda), 2018 Aug 30. PMID 29991509, Free PMC Article
    2. Drosophila spermatid individualization is sensitive to temperature and fatty acid metabolism. Ben-David G, et al. Spermatogenesis, 2015 Jan-Apr. PMID 26413411, Free PMC Article
    3. Metabolism of sphingosine 1-phosphate and lysophosphatidic acid: a genome wide analysis of gene expression in Drosophila. Renault AD, et al. Mech Dev, 2002 Dec. PMID 14516700
    4. A sexually transmitted sugar orchestrates reproductive responses to nutritional stress. Kim SJ, et al. Nat Commun, 2024 Oct 1. PMID 39353950, Free PMC Article
    5. Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the immune deficiency signaling pathway. Deshpande R, et al. G3 (Bethesda), 2022 Nov 4. PMID 35781508, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables calcium-dependent phospholipase A2 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phospholipase A2 activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in arachidonate secretion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phospholipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30503-PA
    CG30503-PB
    NP_001137612.1
    NP_724557.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      7443824..7445792 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001144140.3 → NP_001137612.1  uncharacterized protein Dmel_CG30503, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137612.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JX94
      Conserved Domains (1) summary
      pfam05826
      Location:28 → 121
      Phospholip_A2_2; Phospholipase A2

    2. NM_165524.3 → NP_724557.1  uncharacterized protein Dmel_CG30503, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724557.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JX94
      Related
      FBpp0088075
      Conserved Domains (1) summary
      pfam05826
      Location:28 → 121
      Phospholip_A2_2; Phospholipase A2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JX94 Q7JX94

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