Ift70a1 intraflagellar transport 70A1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ift70a1provided by RGD
Official Full Name: intraflagellar transport 70A1provided by RGD
Primary source: RGD:2318157
See related: AllianceGenome:RGD:2318157
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ttc30a; Ttc30a1
Summary: Predicted to enable intraciliary transport particle B binding activity. Predicted to be involved in intraciliary transport. Predicted to be located in centrosome and cilium. Predicted to be part of intraciliary transport particle B. Predicted to be active in axonemal microtubule. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Testes (RPKM 52.1), Kidney (RPKM 26.9) and 9 other tissues See more
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Genomic context

Location:: 3q23

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (81309158..81312612, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (60901896..60905350, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (62803635..62810291, complement)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

RH138121 (e-PCR)
- UniSTS:220208

RH133128 (e-PCR)
- UniSTS:216411

D3Rat179 (e-PCR), detects polymorphism
- UniSTS:227575

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables intraciliary transport particle B binding	IBA Inferred from Biological aspect of Ancestor more info
enables intraciliary transport particle B binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in intraciliary transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intraciliary transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in axonemal microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in axonemal microtubule	IEA Inferred from Electronic Annotation more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in cilium	ISO Inferred from Sequence Orthology more info
part_of intraciliary transport particle B	IBA Inferred from Biological aspect of Ancestor more info
part_of intraciliary transport particle B	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: tetratricopeptide repeat domain 30B

Names: tetratricopeptide repeat domain 30A; tetratricopeptide repeat domain 30A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001271494.1 → NP_001258423.1 tetratricopeptide repeat domain 30B

See identical proteins and their annotated locations for NP_001258423.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/TrEMBL

A0A0H2UHX9, A0A8I5ZT76, A6HMG6

Conserved Domains (3) summary

sd00006
Location:44 → 74

TPR; TPR repeat [structural motif]

pfam13414
Location:152 → 215

TPR_11; TPR repeat

pfam14559
Location:21 → 87

TPR_19; Tetratricopeptide repeat