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    Dcps Decapping enzyme, scavenger [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40711, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dcpsprovided by FlyBase
    Official Full Name
    Decapping enzyme, scavengerprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037372
    Locus tag
    Dmel_CG2091
    See related
    AllianceGenome:FB:FBgn0037372
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2091; Dmel\CG2091
    Summary
    Predicted to enable 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity and RNA 7-methylguanosine cap binding activity. Predicted to be involved in deadenylation-dependent decapping of nuclear-transcribed mRNA. Predicted to be active in P-body and nucleus. Is expressed in organism. Orthologous to human DCPS (decapping enzyme, scavenger). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Dcps in Genome Data Viewer
    Location:
    83C2-83C2; 3-47.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5753318..5754774, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1579040..1580496, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Symplekin Neighboring gene MLF1-adaptor molecule Neighboring gene Secretory 8 Neighboring gene uncharacterized protein Neighboring gene jagunal

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spotted-dick, a zinc-finger protein of Drosophila required for expression of Orc4 and S phase. Page AR, et al. EMBO J, 2005 Dec 21. PMID 16369566, Free PMC Article
    2. Patterns of gene expression during Drosophila mesoderm development. Furlong EE, et al. Science, 2001 Aug 31. PMID 11486054
    3. A systems biology analysis of the Drosophila phagosome. Stuart LM, et al. Nature, 2007 Jan 4. PMID 17151602
    4. Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. Krauchunas AR, et al. Dev Biol, 2012 Oct 1. PMID 22884528, Free PMC Article
    5. Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster. Okada H, et al. Nat Commun, 2016 Sep 1. PMID 27582081, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA 7-methylguanosine cap binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in P-body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    decapping enzyme, scavenger
    Names
    CG2091-PA
    Dcps-PA
    NP_649582.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5753318..5754774 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141325.3 → NP_649582.1  decapping enzyme, scavenger [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649582.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VNH5
      Related
      FBpp0078327
      Conserved Domains (3) summary
      COG5075
      Location:17 → 307
      COG5075; Uncharacterized conserved protein [Function unknown]
      pfam05652
      Location:15 → 124
      DcpS; Scavenger mRNA decapping enzyme (DcpS) N-terminal
      pfam11969
      Location:155 → 260
      DcpS_C; Scavenger mRNA decapping enzyme C-term binding
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VNH5 Q9VNH5

    Gene LinkOut

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