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    CG2113 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38356, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2113provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035384
    Locus tag
    Dmel_CG2113
    See related
    AllianceGenome:FB:FBgn0035384
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT18037; Dmel\CG2113
    Summary
    Predicted to enable actin binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be located in actin cytoskeleton. Orthologous to human ABRA (actin binding Rho activating protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2113 in Genome Data Viewer
    Location:
    63A2-63A2; 3-5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (2995172..2996155)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (2995172..2996155)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44530 Neighboring gene Carnitine palmitoyltransferase 2 Neighboring gene FMRFamide Receptor Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quantitative evolutionary genomics: differential gene expression and male reproductive success in Drosophila melanogaster. Drnevich JM, et al. Proc Biol Sci, 2004 Nov 7. PMID 15539352, Free PMC Article
    2. Direct targets of the D. melanogaster DSXF protein and the evolution of sexual development. Luo SD, et al. Development, 2011 Jul. PMID 21652649, Free PMC Article
    3. Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development. Zheng Y, et al. BMC Genomics, 2023 May 26. PMID 37237333, Free PMC Article
    4. Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. Leung W, et al. G3 (Bethesda), 2015 Mar 4. PMID 25740935, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables actin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in actin cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in sarcomere IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2113-PA
    CG2113-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      2995172..2996155
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_139500.2 → NP_647757.2  uncharacterized protein Dmel_CG2113, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_647757.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7JWS7, Q9VZW6
      Related
      FBpp0072849
      Conserved Domains (1) summary
      pfam14705
      Location:75 → 148
      Costars; Costars

    2. NM_001274417.1 → NP_001261346.1  uncharacterized protein Dmel_CG2113, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261346.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PH37, Q7JWS7
      Conserved Domains (1) summary
      pfam14705
      Location:71 → 144
      Costars; Costars
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PH37 M9PH37
    Q7JWS7 Q7JWS7
    Q9VZW6 Q9VZW6

    Gene LinkOut

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