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    CG2260 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31732, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2260provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030000
    Locus tag
    Dmel_CG2260
    See related
    AllianceGenome:FB:FBgn0030000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2260
    Summary
    Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in organism. Orthologous to human WDR46 (WD repeat domain 46). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2260 in Genome Data Viewer
    Location:
    7D6-7D6; 1-22 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (8119082..8121147, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (8013115..8015180, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Glutamate-cysteine ligase catalytic subunit Neighboring gene uncharacterized protein Neighboring gene cypher Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. Edlich-Muth C, et al. J Mol Biol, 2015 May 22. PMID 25813344, Free PMC Article
    2. Comparative interactome analysis of α-arrestin families in human and Drosophila. Lee KT, et al. Elife, 2024 Jan 25. PMID 38270169, Free PMC Article
    3. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article
    4. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
    5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2260-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      8119082..8121147 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132213.2 → NP_572441.1  uncharacterized protein Dmel_CG2260 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572441.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W3K3
      Related
      FBpp0071142
      Conserved Domains (4) summary
      smart01033
      Location:422 → 500
      BING4CT; BING4CT (NUC141) domain
      COG2319
      Location:181 → 371
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:181 → 210
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:177 → 398
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W3K3 Q9W3K3

    Gene LinkOut

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