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    proV glycine betaine/carnitine/choline/L-proline ABC transporter ATP-binding protein ProV [ Mycobacterium tuberculosis H37Rv ]

    Gene ID: 886293, updated on 6-Oct-2023

    Summary

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    Gene symbol
    proV
    Gene description
    glycine betaine/carnitine/choline/L-proline ABC transporter ATP-binding protein ProV
    Locus tag
    Rv3758c
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mycobacterium tuberculosis H37Rv (strain: H37Rv, type-material: type strain of Mycobacterium tuberculosis)
    Lineage
    Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
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    Genomic context

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    Sequence:
    NC_000962.3 (4203287..4204417, complement)

    NC_000962.3Genomic Context describing neighboring genes Neighboring gene prephenate dehydrogenase TyrA Neighboring gene hypothetical protein Neighboring gene glycine betaine/carnitine/choline/L-proline ABC transporter permease ProZ Neighboring gene glycine betaine/carnitine/choline/L-proline ABC transporter permease ProW Neighboring gene glycine betaine/carnitine/choline/L-proline ABC transporter substrate-binding lipoprotein ProX Neighboring gene membrane protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000962.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Glycine betaine uptake by the ProXVWZ ABC transporter contributes to the ability of Mycobacterium tuberculosis to initiate growth in human macrophages. Price CT, et al. J Bacteriol, 2008 Jun. PMID 18390665, Free PMC Article
    2. TubercuList--10 years after. Lew JM, et al. Tuberculosis (Edinb), 2011 Jan. PMID 20980199
    3. Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv. Camus JC, et al. Microbiology (Reading), 2002 Oct. PMID 12368430
    4. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Cole ST, et al. Nature, 1998 Jun 11. PMID 9634230

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. role of proXVWZ in allowing M. tuberculosis to obtain betaine from host macrophages and thereby contributes to early steps in colonizing this niche is reported
      Title: Glycine betaine uptake by the ProXVWZ ABC transporter contributes to the ability of Mycobacterium tuberculosis to initiate growth in human macrophages.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    glycine betaine/carnitine/choline/L-proline ABC transporter ATP-binding protein ProV

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000962.3 Reference assembly

      Range
      4203287..4204417 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_218275.1 glycine betaine/carnitine/choline/L-proline ABC transporter ATP-binding protein ProV [Mycobacterium tuberculosis H37Rv]

      See identical proteins and their annotated locations for NP_218275.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A655I4C8
      Conserved Domains (1) summary
      COG1125
      Location:1 → 327
      OpuBA; ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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