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    CG4645 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32244, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4645provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030435
    Locus tag
    Dmel_CG4645
    See related
    AllianceGenome:FB:FBgn0030435
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4645
    Summary
    Predicted to enable small GTPase binding activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Is expressed in adult head. Orthologous to human YIPF1 (Yip1 domain family member 1) and YIPF2 (Yip1 domain family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4645 in Genome Data Viewer
    Location:
    11D1-11D2; 1-41 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (12909953..12912070)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (12803986..12806103)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L49 Neighboring gene BRMS1 transcriptional repressor Neighboring gene long non-coding RNA:CR45625 Neighboring gene long non-coding RNA:CR45626

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Drosophila radish gene encodes a protein required for anesthesia-resistant memory. Folkers E, et al. Proc Natl Acad Sci U S A, 2006 Nov 14. PMID 17088531, Free PMC Article
    2. Cell-Surface Proteomic Profiling in the Fly Brain Uncovers Wiring Regulators. Li J, et al. Cell, 2020 Jan 23. PMID 31955847, Free PMC Article
    3. Anion-sensitive fluorophore identifies the Drosophila swell-activated chloride channel in a genome-wide RNA interference screen. Stotz SC, et al. PLoS One, 2012. PMID 23056495, Free PMC Article
    4. A genetic screen in Drosophila reveals the role of fucosylation in host susceptibility to Candida infection. Glittenberg MT, et al. Dis Model Mech, 2022 May 1. PMID 35142345, Free PMC Article
    5. RIP-seq analysis of eukaryotic Sm proteins identifies three major categories of Sm-containing ribonucleoproteins. Lu Z, et al. Genome Biol, 2014 Jan 7. PMID 24393626, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4645-PA
    CG4645-PB
    CG4645-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      12909953..12912070
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132613.3 → NP_572841.1  uncharacterized protein Dmel_CG4645, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572841.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TM7, Q9VYI1
      Related
      FBpp0073525
      Conserved Domains (1) summary
      pfam04893
      Location:149 → 310
      Yip1; Yip1 domain

    2. NM_001298242.1 → NP_001285171.1  uncharacterized protein Dmel_CG4645, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285171.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TM7, Q9VYI1
      Conserved Domains (1) summary
      pfam04893
      Location:149 → 310
      Yip1; Yip1 domain

    3. NM_001298243.1 → NP_001285172.1  uncharacterized protein Dmel_CG4645, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285172.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95TM7, Q9VYI1
      Conserved Domains (1) summary
      pfam04893
      Location:149 → 310
      Yip1; Yip1 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VYI1 Q9VYI1

    Gene LinkOut

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