U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SKIP Shal K[+] channel interacting protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42601, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SKIPprovided by FlyBase
    Official Full Name
    Shal K[+] channel interacting proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051163
    Locus tag
    Dmel_CG31163
    See related
    AllianceGenome:FB:FBgn0051163
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13863; CG13864; CG31163; CG5736; CG7086; CG7087; Dmel\CG31163
    Summary
    Involved in sensory perception of smell. Is expressed in several structures, including central brain primordium; dorsal epidermis primordium; embryonic/larval midgut primordium; ganglia; and gut section. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Orthologous to human SASH1 (SAM and SH3 domain containing 1) and SAMD5 (sterile alpha motif domain containing 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SKIP in Genome Data Viewer
    Location:
    94A2-94A4; 3-74 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (22133830..22296126)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (17959552..18121848)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 94c Neighboring gene long non-coding RNA:CR45224 Neighboring gene GLD2 poly(A) polymerase Neighboring gene mir-1010 stem loop Neighboring gene pseudo Neighboring gene pseudo

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Regulation of subcellular dendritic synapse specificity by axon guidance cues. Sales EC, et al. Elife, 2019 Apr 23. PMID 31012844, Free PMC Article
    2. The mirtron miR-1010 functions in concert with its host gene SKIP to balance elevation of nAcRβ2. Amourda C, et al. Sci Rep, 2020 Feb 3. PMID 32015391, Free PMC Article
    3. The CSL proteins, versatile transcription factors and context dependent corepressors of the notch signaling pathway. Contreras-Cornejo H, et al. Cell Div, 2016. PMID 27708688, Free PMC Article
    4. Fast inactivation of Shal (K(v)4) K+ channels is regulated by the novel interactor SKIP3 in Drosophila neurons. Diao F, et al. Mol Cell Neurosci, 2009 Sep. PMID 19463952, Free PMC Article
    5. The genetic basis of variation in Drosophila melanogaster mating behavior. Yamamoto A, et al. iScience, 2024 May 17. PMID 38766354, Free PMC Article

    See all (62) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in regulation of intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sensory perception of smell IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    shal K[+] channel interacting protein
    Names
    CG31163-PB
    CG31163-PE
    CG31163-PF
    CG31163-PG
    CG31163-PH
    CG31163-PI
    CG31163-PJ
    SKIP-PB
    SKIP-PE
    SKIP-PF
    SKIP-PG
    SKIP-PH
    SKIP-PI
    SKIP-PJ
    skal K[+] channel interacting protein

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      22133830..22296126
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001260304.2 → NP_001247233.1  shal K[+] channel interacting protein, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247233.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KI30
      Conserved Domains (4) summary
      cd09527
      Location:4 → 65
      SAM_Samd5; SAM domain of Samd5 subfamily
      smart00454
      Location:850 → 913
      SAM; Sterile alpha motif
      cl15755
      Location:854 → 912
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17036
      Location:769 → 822
      SH3; Src Homology 3 domain superfamily

    2. NM_001275899.1 → NP_001262828.1  shal K[+] channel interacting protein, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262828.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHM3
      Conserved Domains (4) summary
      cd09527
      Location:4 → 65
      SAM_Samd5; SAM domain of Samd5 subfamily
      smart00454
      Location:813 → 876
      SAM; Sterile alpha motif
      cl15755
      Location:817 → 875
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17036
      Location:732 → 785
      SH3; Src Homology 3 domain superfamily

    3. NM_001260305.1 → NP_001247234.1  shal K[+] channel interacting protein, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247234.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K6C1
      Conserved Domains (4) summary
      cd09527
      Location:4 → 65
      SAM_Samd5; SAM domain of Samd5 subfamily
      smart00454
      Location:813 → 876
      SAM; Sterile alpha motif
      cl15755
      Location:817 → 875
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17036
      Location:732 → 785
      SH3; Src Homology 3 domain superfamily

    4. NM_001043277.3 → NP_001036742.2  shal K[+] channel interacting protein, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036742.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KI30
      Conserved Domains (4) summary
      cd09527
      Location:4 → 65
      SAM_Samd5; SAM domain of Samd5 subfamily
      smart00454
      Location:850 → 913
      SAM; Sterile alpha motif
      cl15755
      Location:854 → 912
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17036
      Location:769 → 822
      SH3; Src Homology 3 domain superfamily

    5. NM_169997.5 → NP_732703.1  shal K[+] channel interacting protein, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732703.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZS0, Q8T9B0
      Related
      FBpp0083595
      Conserved Domains (4) summary
      cd09527
      Location:4 → 65
      SAM_Samd5; SAM domain of Samd5 subfamily
      smart00454
      Location:738 → 801
      SAM; Sterile alpha motif
      cl15755
      Location:742 → 800
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17036
      Location:657 → 710
      SH3; Src Homology 3 domain superfamily

    6. NM_001275898.1 → NP_001262827.1  shal K[+] channel interacting protein, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262827.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KHV7
      Conserved Domains (4) summary
      cd09527
      Location:4 → 65
      SAM_Samd5; SAM domain of Samd5 subfamily
      smart00454
      Location:738 → 801
      SAM; Sterile alpha motif
      cl15755
      Location:742 → 800
      SAM_superfamily; SAM (Sterile alpha motif )
      cl17036
      Location:657 → 710
      SH3; Src Homology 3 domain superfamily

    7. NM_001275897.1 → NP_001262826.1  shal K[+] channel interacting protein, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001262826.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KH49
      Conserved Domains (2) summary
      cd09527
      Location:4 → 65
      SAM_Samd5; SAM domain of Samd5 subfamily
      smart00454
      Location:7 → 65
      SAM; Sterile alpha motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K6C1 A0A0B4K6C1
    A0A0B4KH49 A0A0B4KH49
    A0A0B4KHM3 A0A0B4KHM3
    A0A0B4KHV7 A0A0B4KHV7
    Q0KI30 Q0KI30
    Q8SZS0 Q8SZS0
    Q8T9B0 Q8T9B0
    Q95RX2 Q95RX2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools