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    lectin-28C lectin-28C [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 53542, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lectin-28Cprovided by FlyBase
    Official Full Name
    lectin-28Cprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040099
    Locus tag
    Dmel_CG7106
    See related
    AllianceGenome:FB:FBgn0040099
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    AC 004723A; AC004723a; CG7106; Dmel\CG7106
    Summary
    Predicted to enable galactose binding activity. Predicted to be involved in opsonization. Predicted to be located in extracellular space. Is expressed in adult heart and eye. Human ortholog(s) of this gene implicated in 3MC syndrome 3; asthma; lung disease (multiple); respiratory syncytial virus infectious disease; and rhinitis. Orthologous to several human genes including COLEC10 (collectin subfamily member 10); SFTPA1 (surfactant protein A1); and SFTPA2 (surfactant protein A2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See lectin-28C in Genome Data Viewer
    Location:
    28D2-28D2; 2-29 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7857077..7860120)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7857077..7860120)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene TweedleE Neighboring gene Proctolin Neighboring gene long non-coding RNA:CR45364

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables galactose binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in opsonization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    lectin-28C
    Names
    CG7106-PB
    CG7106-PC
    Lectin28C
    lectin-28C-PB
    lectin-28C-PC
    NP_001285727.1
    • complex mutation
    NP_652636.2
    • complex mutation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7857077..7860120
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298798.1 → NP_001285727.1  lectin-28C, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285727.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4U3Q2, Q9VLW1
      Conserved Domains (2) summary
      cd00037
      Location:160 → 260
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
      pfam09074
      Location:12 → 134
      Mer2; Mer2

    2. NM_144379.3 → NP_652636.2  lectin-28C, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652636.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4U3Q2, Q9VLW1
      Conserved Domains (2) summary
      cd00037
      Location:160 → 260
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
      pfam09074
      Location:12 → 134
      Mer2; Mer2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VLW1 Q9VLW1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials