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    Cyp6a16 Cytochrome P450 6a16 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 19836250, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cyp6a16provided by FlyBase
    Official Full Name
    Cytochrome P450 6a16provided by FlyBase
    Primary source
    FLYBASE:FBgn0031726
    Locus tag
    Dmel_CG7249
    See related
    AllianceGenome:FB:FBgn0031726
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    6a16; CG7249; CR7249; Cyp6a16p; Cyp6a16Psi; Dmel\CG7249
    Summary
    Predicted to enable heme binding activity and iron ion binding activity. Is expressed in amnioserosa; embryonic Malpighian tubule; and yolk nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Cyp6a16 in Genome Data Viewer
    Location:
    25F1-25F1; 2-17 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5620615..5623762, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5620615..5623762, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Dpr-interacting protein eta Neighboring gene long non-coding RNA:CR44795 Neighboring gene long non-coding RNA:CR44796 Neighboring gene Dpr-interacting protein theta Neighboring gene long non-coding RNA:CR44822 Neighboring gene mir-959 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nonlinear expression patterns and multiple shifts in gene network interactions underlie robust phenotypic change in Drosophila melanogaster selected for night sleep duration. Souto-Maior C, et al. PLoS Comput Biol, 2023 Aug. PMID 37561813, Free PMC Article
    2. Integrative genome-wide analysis of dopaminergic neuron-specific PARIS expression in Drosophila dissects recognition of multiple PPAR-γ associated gene regulation. Yazar V, et al. Sci Rep, 2021 Nov 2. PMID 34728675, Free PMC Article
    3. The identification of protein and RNA interactors of the splicing factor Caper in the adult Drosophila nervous system. Titus MB, et al. Front Mol Neurosci, 2023. PMID 37435576, Free PMC Article
    4. The molecular evolution of cytochrome P450 genes within and between drosophila species. Good RT, et al. Genome Biol Evol, 2014 Apr 20. PMID 24751979, Free PMC Article
    5. The cytochrome P450 gene superfamily in Drosophila melanogaster: annotation, intron-exon organization and phylogeny. Tijet N, et al. Gene, 2001 Jan 10. PMID 11179683

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT enables monooxygenase activity IKR
    Inferred from Key Residues
    more info
    		 PubMed 
    NOT enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IKR
    Inferred from Key Residues
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome P450 6a16
    Names
    CG7249-PB
    CG7249-PC
    Cyp6a16-PB
    Cyp6a16-PC
    Cyp6a16Psi
    NP_001285631.1
    • complex mutation, may be evolving pseudogene
    NP_001285632.1
    • complex mutation, may be evolving pseudogene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5620615..5623762 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298702.1 → NP_001285631.1  cytochrome P450 6a16, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285631.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2J9F6
      Conserved Domains (1) summary
      pfam00067
      Location:32 → 492
      p450; Cytochrome P450

    2. NM_001298703.1 → NP_001285632.1  cytochrome P450 6a16, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285632.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2J9F6
      Conserved Domains (1) summary
      pfam00067
      Location:32 → 492
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    X2J9F6 X2J9F6

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