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    ADY3 Ady3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851359, updated on 9-Dec-2024

    Summary

    Official Symbol
    ADY3
    Official Full Name
    Ady3p
    Primary source
    SGD:S000002398
    Locus tag
    YDL239C
    See related
    AllianceGenome:SGD:S000002398; FungiDB:YDL239C; VEuPathDB:YDL239C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in ascospore wall assembly; ascospore-type prospore membrane formation; and mitochondrion inheritance. Located in peroxisome; prospore membrane leading edge; and spindle pole body. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ADY3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (26403..28775, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene GTPase-activating protein LRG1 Neighboring gene guanine deaminase Neighboring gene Aim6p

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in ascospore wall assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in ascospore-type prospore membrane formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrion inheritance IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in mitochondrion inheritance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitotic chromosome condensation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sporulation resulting in formation of a cellular spore IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sporulation resulting in formation of a cellular spore IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in condensed chromosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of condensin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in prospore membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in prospore membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in prospore membrane leading edge HDA PubMed 
    located_in prospore membrane leading edge IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in spindle pole body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in spindle pole body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in spindle pole body IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    Ady3p
    NP_010042.2
    • Protein required for spore wall formation; subunit of leading edge protein (LEP) complex (Ssp1-Ady3-Don1-Irc10) that forms ring-like structure at leading edge of prospore membrane during meiosis II; mediates assembly of LEP complex, formation of ring-like structure via interaction with spindle pole body components, and prospore membrane maturation; also detected in peroxisomes; potentially phosphorylated by Cdc28p; ADY3 has a paralog, CNM67, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      26403..28775 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180299.2NP_010042.2  TPA: Ady3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010042.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRB7, Q07732
      UniProtKB/TrEMBL
      B3LHB5, C7GJQ8, N1P5X2
      Conserved Domains (3) summary
      COG1196
      Location:187520
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK12704
      Location:482603
      PRK12704; phosphodiesterase; Provisional
      pfam11778
      Location:655789
      SID; Septation initiation