CG9240 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG9240provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0030669
Locus tag: Dmel_CG9240
See related: AllianceGenome:FB:FBgn0030669
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-EST:Posey267; Dmel\CG9240
Summary: Predicted to enable endopeptidase activity. Predicted to be involved in protein processing involved in protein targeting to mitochondrion. Predicted to be located in membrane. Predicted to be part of mitochondrial inner membrane peptidase complex. Is expressed in adult head; organism; and spermatozoon. Orthologous to human IMMP1L (inner mitochondrial membrane peptidase subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 13E8-13E8; 1-51 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (15700172..15701259, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (15594205..15595292, complement)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables endopeptidase activity	ISS Inferred from Sequence or Structural Similarity more info
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein processing involved in protein targeting to mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein processing involved in protein targeting to mitochondrion	ISS Inferred from Sequence or Structural Similarity more info
involved_in signal peptide processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of mitochondrial inner membrane peptidase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial inner membrane peptidase complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: uncharacterized protein

Names: CG9240-PA; CG9240-PB

NP_001245694.1

EC 3.4.21.-

NP_573054.2

EC 3.4.21.-

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_004354.4 Reference assembly

Range

15700172..15701259 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_132826.4 → NP_573054.2 uncharacterized protein Dmel_CG9240, isoform A [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_573054.2

Status: REVIEWED

UniProtKB/TrEMBL

Q8SZ24, Q9VXR8

Related

FBpp0073876

Conserved Domains (3) summary

cd06530
Location:31 → 153

S26_SPase_I; The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are ...

TIGR02227
Location:30 → 159

sigpep_I_bact; signal peptidase I, bacterial type

cl10465
Location:81 → 145

Peptidase_S24_S26; The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the ...
NM_001258765.2 → NP_001245694.1 uncharacterized protein Dmel_CG9240, isoform B [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001245694.1

Status: REVIEWED

UniProtKB/TrEMBL

D5A7R5

Conserved Domains (2) summary

cd06530
Location:1 → 115

S26_SPase_I; The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are ...

cl10465
Location:43 → 107

Peptidase_S24_S26; The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the ...