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    Trat1 T cell receptor associated transmembrane adaptor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498075, updated on 9-Dec-2024

    Summary

    Official Symbol
    Trat1provided by RGD
    Official Full Name
    T cell receptor associated transmembrane adaptor 1provided by RGD
    Primary source
    RGD:1563011
    See related
    EnsemblRapid:ENSRNOG00000029564 AllianceGenome:RGD:1563011
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in negative regulation of receptor recycling and positive regulation of T cell receptor signaling pathway. Predicted to act upstream of or within negative regulation of transport and positive regulation of calcium-mediated signaling. Predicted to be located in centriolar satellite; mitotic spindle; and plasma membrane. Predicted to be part of T cell receptor complex. Orthologous to human TRAT1 (T cell receptor associated transmembrane adaptor 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 345.6) and Spleen (RPKM 49.0) See more
    Orthologs
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    Genomic context

    See Trat1 in Genome Data Viewer
    Location:
    11q21
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (65498742..65540823)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (52035750..52077805)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (54619169..54661284)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene resistin like alpha Neighboring gene resistin like beta Neighboring gene uncharacterized LOC134480996 Neighboring gene MORC family CW-type zinc finger 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC125004

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    part_of T cell receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of T cell receptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centriolar satellite IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    T cell receptor associated transmembrane adaptor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037981.1NP_001033070.1  T cell receptor associated transmembrane adaptor 1

      See identical proteins and their annotated locations for NP_001033070.1

      Status: PROVISIONAL

      Source sequence(s)
      BC111081
      UniProtKB/TrEMBL
      A6IQV8, F7F6T0
      Related
      ENSRNOP00000056668.2, ENSRNOT00000059924.4
      Conserved Domains (1) summary
      pfam15330
      Location:23120
      SIT; SHP2-interacting transmembrane adaptor protein, SIT

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      65498742..65540823
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)