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    ERP3 Erp3p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851544, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ERP3
    Official Full Name
    Erp3p
    Primary source
    SGD:S000002176
    Locus tag
    YDL018C
    See related
    AllianceGenome:SGD:S000002176; FungiDB:YDL018C; VEuPathDB:YDL018C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in several processes, including Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and protein retention in ER lumen. Located in endoplasmic reticulum. Orthologous to several human genes including TMED7-TICAM2 (TMED7-TICAM2 readthrough); TMED1 (transmembrane p24 trafficking protein 1); and TMED3 (transmembrane p24 trafficking protein 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ERP3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (422833..423510, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene stress-regulated transcription factor RPN4 Neighboring gene oxysterol-binding protein related protein OSH2 Neighboring gene serine/threonine protein kinase CDC7 Neighboring gene trans-2-enoyl-CoA reductase (NADPH) TSC13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex. Marzioch M, et al. Mol Biol Cell, 1999 Jun. PMID 10359606, Free PMC Article
    2. The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae. Springer S, et al. Proc Natl Acad Sci U S A, 2000 Apr 11. PMID 10737764, Free PMC Article
    3. Isoform-selective oligomer formation of Saccharomyces cerevisiae p24 family proteins. Hirata R, et al. J Biol Chem, 2013 Dec 27. PMID 24217251, Free PMC Article
    4. Identification of aluminium transport-related genes via genome-wide phenotypic screening of Saccharomyces cerevisiae. Tun NM, et al. Metallomics, 2014 Aug. PMID 24926745
    5. Vps39 Interacts with Tom40 to Establish One of Two Functionally Distinct Vacuole-Mitochondria Contact Sites. González Montoro A, et al. Dev Cell, 2018 Jun 4. PMID 29870720

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein retention in ER lumen IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport ISA
    Inferred from Sequence Alignment
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Erp3p
    NP_010266.1
    • Protein with similarity to Emp24p and Erv25p; member of the p24 family involved in ER to Golgi transport

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      422833..423510 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180077.1 → NP_010266.1  TPA: Erp3p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010266.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRX2, Q12403
      UniProtKB/TrEMBL
      C7GW61, C8Z4Q1
      Conserved Domains (1) summary
      pfam01105
      Location:23 → 218
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12403.1

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