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    Ankrd37 ankyrin repeat domain 37 [ Mus musculus (house mouse) ]

    Gene ID: 654824, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ankrd37provided by MGI
    Official Full Name
    ankyrin repeat domain 37provided by MGI
    Primary source
    MGI:MGI:3603344
    See related
    Ensembl:ENSMUSG00000050914 AllianceGenome:MGI:3603344
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Located in cytoplasm and male germ cell nucleus. Is expressed in several structures, including adipose tissue; bone; liver; lung; and spleen. Orthologous to human ANKRD37 (ankyrin repeat domain 37). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 4.0), CNS E14 (RPKM 2.7) and 27 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ankrd37 in Genome Data Viewer
    Location:
    8 B1.1; 8 25.99 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (46449945..46452904, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (45996908..46000414, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene PDZ and LIM domain 3 Neighboring gene STARR-seq mESC enhancer starr_21375 Neighboring gene STARR-positive B cell enhancer mm9_chr8:47020100-47020401 Neighboring gene coiled-coil domain containing 110 Neighboring gene cilia and flagella associated protein 96 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:47060555-47060664 Neighboring gene STARR-positive B cell enhancer ABC_E10496 Neighboring gene UFM1-specific peptidase 2 Neighboring gene Lrp2 binding protein Neighboring gene sorting nexin 25 Neighboring gene STARR-seq mESC enhancer starr_21377 Neighboring gene STARR-positive B cell enhancer ABC_E10497 Neighboring gene predicted gene 15634

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mouse Fem1b interacts with and induces ubiquitin-mediated degradation of Ankrd37. Shi YQ, et al. Gene, 2011 Oct 10. PMID 21723927
    2. BMPR2 is required for postimplantation uterine function and pregnancy maintenance. Nagashima T, et al. J Clin Invest, 2013 Jun. PMID 23676498, Free PMC Article
    3. Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs. Pan J, et al. Am J Reprod Immunol, 2015 Sep. PMID 26073538
    4. Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling. Yorgan TA, et al. Bone, 2019 Oct. PMID 31202927
    5. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in male germ cell nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    ankyrin repeat domain-containing protein 37

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039562.2 → NP_001034651.1  ankyrin repeat domain-containing protein 37 isoform a

      See identical proteins and their annotated locations for NP_001034651.1

      Status: VALIDATED

      Source sequence(s)
      AC114558
      Consensus CDS
      CCDS22285.1
      UniProtKB/Swiss-Prot
      Q569N2, Q8CHS0
      Related
      ENSMUSP00000056828.9, ENSMUST00000053558.10
      Conserved Domains (3) summary
      cd00204
      Location:10 → 116
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam13637
      Location:66 → 116
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:30 → 61
      ANK; ANK repeat [structural motif]

    2. NM_001404726.1 → NP_001391655.1  ankyrin repeat domain-containing protein 37 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC114558

    3. NM_001404727.1 → NP_001391656.1  ankyrin repeat domain-containing protein 37 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC114558

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      46449945..46452904 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q569N2.1 GenPept UniProtKB/Swiss-Prot:Q569N2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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