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    RPL19A ribosomal 60S subunit protein L19A [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852379, updated on 9-Dec-2024

    Summary

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    Official Symbol
    RPL19A
    Official Full Name
    ribosomal 60S subunit protein L19A
    Primary source
    SGD:S000002156
    Locus tag
    YBR084C-A
    See related
    AllianceGenome:SGD:S000002156; FungiDB:YBR084C-A; VEuPathDB:YBR084C-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Part of cytosolic large ribosomal subunit. Orthologous to human RPL19 (ribosomal protein L19). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See RPL19A in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_001134.8 (414186..415261, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Tec1p Neighboring gene trifunctional formate-tetrahydrofolate ligase/methenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase MIS1 Neighboring gene ADP/ATP carrier protein AAC3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nucleotide sequence and characterization of the Saccharomyces cerevisiae RPL19A gene encoding a homolog of the mammalian ribosomal protein L19. Song JM, et al. Yeast, 1995 Apr 15. PMID 7785339
    2. The Functional Role of eL19 and eB12 Intersubunit Bridge in the Eukaryotic Ribosome. Kisly I, et al. J Mol Biol, 2016 May 22. PMID 27038511, Free PMC Article
    3. Functional analysis of a duplicated linked pair of ribosomal protein genes in Saccharomyces cerevisiae. Donovan DM, et al. Mol Cell Biol, 1990 Nov. PMID 2233736, Free PMC Article
    4. Organization and characterization of the two yeast ribosomal protein YL19 genes. Song JM, et al. Curr Genet, 1996 Sep. PMID 8781168
    5. Functional Interactions of Ribosomal Intersubunit Bridges in Saccharomyces cerevisiae. Tamm T, et al. Genetics, 2019 Dec. PMID 31649153, Free PMC Article

    See all (101) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of cytosolic large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal 60S subunit protein L19A
    NP_009641.1
    • Ribosomal 60S subunit protein L19A; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal; homologous to mammalian ribosomal protein L19, no bacterial homolog; RPL19A has a paralog, RPL19B, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      414186..415261 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180057.1 → NP_009641.1  TPA: ribosomal 60S subunit protein L19A [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009641.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VPX3, P05735, P0CX82, P0CX83
      UniProtKB/TrEMBL
      A6ZKS1, B3LN67, C8Z3W9, G2W991
      Conserved Domains (1) summary
      cd01417
      Location:4 → 166
      Ribosomal_L19e_E; Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P0CX82.1
    P0CX83.1

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