U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ERP6 Erp6p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852882, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ERP6
    Official Full Name
    Erp6p
    Primary source
    SGD:S000002970
    Locus tag
    YGL002W
    See related
    AllianceGenome:SGD:S000002970; FungiDB:YGL002W; VEuPathDB:YGL002W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in endoplasmic reticulum and mitochondrion. Orthologous to human TMED4 (transmembrane p24 trafficking protein 4) and TMED9 (transmembrane p24 trafficking protein 9). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ERP6 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (494517..495167)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene Rpn14p Neighboring gene Cdh1p Neighboring gene sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) Neighboring gene protein-lysine N-methyltransferase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex. Marzioch M, et al. Mol Biol Cell, 1999 Jun. PMID 10359606, Free PMC Article
    2. The p24 proteins are not essential for vesicular transport in Saccharomyces cerevisiae. Springer S, et al. Proc Natl Acad Sci U S A, 2000 Apr 11. PMID 10737764, Free PMC Article
    3. The GOLD domain, a novel protein module involved in Golgi function and secretion. Anantharaman V, et al. Genome Biol, 2002. PMID 12049664, Free PMC Article
    4. Isoform-selective oligomer formation of Saccharomyces cerevisiae p24 family proteins. Hirata R, et al. J Biol Chem, 2013 Dec 27. PMID 24217251, Free PMC Article
    5. Transcriptional divergence plays a role in the rewiring of protein interaction networks after gene duplication. Gagnon-Arsenault I, et al. J Proteomics, 2013 Apr 9. PMID 23063722

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Erp6p
    NP_011513.1
    • Member of the p24 family involved in ER to Golgi transport; similar to Emp24p and Erv25p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; ERP6 has a paralog, ERP1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      494517..495167
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180867.1 → NP_011513.1  TPA: Erp6p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011513.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUD6, E9P916, P53198
      UniProtKB/TrEMBL
      A6ZUZ1, B3LIL7, B5VIW0, C7GK70, C8Z8P3, G2WE92, N1P5M4
      Conserved Domains (1) summary
      pfam01105
      Location:19 → 210
      EMP24_GP25L; emp24/gp25L/p24 family/GOLD
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53198.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous