RIB7 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [Saccharomyces cerevisiae S288C] - Gene

Summary

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Official Symbol: RIB7
Official Full Name: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
Primary source: SGD:S000000357
Locus tag: YBR153W
See related: AllianceGenome:SGD:S000000357; FungiDB:YBR153W; VEuPathDB:YBR153W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables 5-amino-6-(5-phosphoribosylamino)uracil reductase activity. Involved in riboflavin biosynthetic process. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See RIB7 in Genome Data Viewer

Location:: chromosome: II

Exon count:: 1

Sequence:: Chromosome: II; NC_001134.8 (547460..548194)

Chromosome II - NC_001134.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_001134.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by SGD

Function	Evidence Code	Pubs
enables 5-amino-6-(5-phosphoribosylamino)uracil reductase activity	IDA Inferred from Direct Assay more info	PubMed
enables 5-amino-6-(5-phosphoribosylamino)uracil reductase activity	IEA Inferred from Electronic Annotation more info
enables 5-amino-6-(5-phosphoribosylamino)uracil reductase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables NADP binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in riboflavin biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in riboflavin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase

NP_009711.3

EC 1.1.1.302

Diaminohydroxyphoshoribosylaminopyrimidine deaminase; catalyzes the second step of the riboflavin biosynthesis pathway

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_001134.8 Reference assembly

Range

547460..548194

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001178501.3 → NP_009711.3 TPA: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [Saccharomyces cerevisiae S288C]

See identical proteins and their annotated locations for NP_009711.3

Status: REVIEWED

UniProtKB/Swiss-Prot

D6VQE8, P33312

UniProtKB/TrEMBL

G2W9F5, N1PAT9

Conserved Domains (1) summary

TIGR00227
Location:28 → 241

ribD_Cterm; riboflavin-specific deaminase C-terminal domain