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    ATP11 Atp11p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855401, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ATP11
    Official Full Name
    Atp11p
    Primary source
    SGD:S000005259
    Locus tag
    YNL315C
    See related
    AllianceGenome:SGD:S000005259; FungiDB:YNL315C; VEuPathDB:YNL315C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables unfolded protein binding activity. Involved in mitochondrial proton-transporting ATP synthase complex assembly. Located in mitochondrion. Orthologous to human ATPAF1 (ATP synthase mitochondrial F1 complex assembly factor 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ATP11 in Genome Data Viewer
    Location:
    chromosome: XIV
    Exon count:
    1
    Sequence:
    Chromosome: XIV; NC_001146.8 (43324..44280, complement)

    Chromosome XIV - NC_001146.8Genomic Context describing neighboring genes Neighboring gene cleavage polyadenylation factor subunit PFS2 Neighboring gene prephenate dehydratase PHA2 Neighboring gene Dal82p Neighboring gene tetratricopeptide repeat-containing protein EMW1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001146.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Bacterial production and characterization of ATP11, a yeast protein required for mitochondrial F1-ATPase assembly. White M, et al. Arch Biochem Biophys, 1995 May 10. PMID 7771799
    2. Identification of functional domains in Atp11p. Protein required for assembly of the mitochondrial F1-ATPase in yeast. Wang ZG, et al. J Biol Chem, 1996 Mar 1. PMID 8617760
    3. A purified subfragment of yeast Atp11p retains full molecular chaperone activity. Hinton A, et al. J Biol Chem, 2003 Sep 5. PMID 12829692
    4. An accessible hydrophobic surface is a key element of the molecular chaperone action of Atp11p. Sheluho D, et al. J Biol Chem, 2001 Oct 26. PMID 11522798
    5. The assembly factor Atp11p binds to the beta-subunit of the mitochondrial F(1)-ATPase. Wang ZG, et al. J Biol Chem, 2000 Feb 25. PMID 10681564

    See all (70) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables unfolded protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial proton-transporting ATP synthase complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial proton-transporting ATP synthase complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitochondrial proton-transporting ATP synthase complex assembly IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in mitochondrion organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein-containing complex assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Atp11p
    NP_014084.1
    • Molecular chaperone; required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase; N-terminally propionylated in vivo

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001146.8 Reference assembly

      Range
      43324..44280 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183153.1 → NP_014084.1  TPA: Atp11p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014084.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W0N0, P32453
      UniProtKB/TrEMBL
      A6ZSG5, B3LPE9, C7GWR2, C8ZGL0, G2WLF4, N1NWG8
      Conserved Domains (1) summary
      pfam06644
      Location:40 → 310
      ATP11; ATP11 protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P32453.1

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