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    Slc22a7 solute carrier family 22 (organic anion transporter), member 7 [ Mus musculus (house mouse) ]

    Gene ID: 108114, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc22a7provided by MGI
    Official Full Name
    solute carrier family 22 (organic anion transporter), member 7provided by MGI
    Primary source
    MGI:MGI:1859559
    See related
    Ensembl:ENSMUSG00000067144 AllianceGenome:MGI:1859559
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NLT; OAT2
    Summary
    Enables alpha-ketoglutarate transmembrane transporter activity and prostaglandin transmembrane transporter activity. Involved in alpha-ketoglutarate transport; prostaglandin transport; and response to stilbenoid. Located in apical plasma membrane. Is expressed in metanephros. Orthologous to human SLC22A7 (solute carrier family 22 member 7). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward kidney adult (RPKM 85.4) See more
    Orthologs
    NEW
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    Genomic context

    See Slc22a7 in Genome Data Viewer
    Location:
    17 C; 17 22.9 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (46743111..46749403, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (46432185..46438477, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 318 Neighboring gene predicted gene 9706 Neighboring gene cysteine-rich protein 3 Neighboring gene predicted gene, 36541 Neighboring gene ribosomal protein L11 pseudogene Neighboring gene tau tubulin kinase 1 Neighboring gene STARR-seq mESC enhancer starr_42667

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC18877

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in alpha-ketoglutarate transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in alpha-ketoglutarate transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in organic anion transport ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within organic anion transport TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in prostaglandin transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in prostaglandin transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in prostaglandin transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in response to stilbenoid IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basal plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basal plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in basolateral plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    solute carrier family 22 member 7
    Names
    mOAT2
    organic anion transporter 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144856.2NP_659105.2  solute carrier family 22 member 7

      See identical proteins and their annotated locations for NP_659105.2

      Status: VALIDATED

      Source sequence(s)
      AK082865, AK143949
      Consensus CDS
      CCDS28829.1
      UniProtKB/Swiss-Prot
      Q3UNX2, Q8BUQ9, Q8K4S9, Q8R0M7, Q8R125, Q91WU2
      UniProtKB/TrEMBL
      A0A0R4J122
      Related
      ENSMUSP00000084234.6, ENSMUST00000087012.7
      Conserved Domains (2) summary
      cd06174
      Location:146511
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      TIGR00898
      Location:11521
      2A0119; cation transport protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      46743111..46749403 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)