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    CG4098 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39854, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4098provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036648
    Locus tag
    Dmel_CG4098
    See related
    AllianceGenome:FB:FBgn0036648
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4098-PA; Dmel\CG4098
    Summary
    Predicted to enable ADP-ribose diphosphatase activity. Is expressed in organism. Orthologous to human NUDT9 (nudix hydrolase 9). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4098 in Genome Data Viewer
    Location:
    73B1-73B1; 3-44 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16608138..16609347, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16601238..16602447, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene spindle defective 2 Neighboring gene Apollo Neighboring gene pseudo Neighboring gene Artemis Neighboring gene Proteasome beta6 subunit Neighboring gene Suppressor of ref(2)P sterility

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. APOLLO, a testis-specific Drosophila ortholog of importin-4, mediates the loading of protamine-like protein Mst77F into sperm chromatin. Emelyanov AV, et al. J Biol Chem, 2023 Oct. PMID 37660905, Free PMC Article
    2. A molecular analysis of transformer, a gene in Drosophila melanogaster that controls female sexual differentiation. McKeown M, et al. Cell, 1987 Feb 13. PMID 3100051
    3. Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity. Moskalev AA, et al. Sci Rep, 2019 Jun 24. PMID 31235842, Free PMC Article
    4. Formation and longevity of chimeric and duplicate genes in Drosophila melanogaster. Rogers RL, et al. Genetics, 2009 Jan. PMID 19015547, Free PMC Article
    5. Chimeric genes as a source of rapid evolution in Drosophila melanogaster. Rogers RL, et al. Mol Biol Evol, 2012 Feb. PMID 21771717, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ADP-ribose diphosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ADP-ribose diphosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nuclear membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4098-PA
    NP_660192.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      16608138..16609347 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_145191.2 → NP_660192.1  uncharacterized protein Dmel_CG4098 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_660192.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MQV8, Q9VV83
      Related
      FBpp0075120
      Conserved Domains (1) summary
      cd03670
      Location:125 → 303
      ADPRase_NUDT9; ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. Like other members of the Nudix hydrolase superfamily of enzymes, it is thought to require a divalent cation, such as Mg2+, for its activity. It also ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MQV8 Q8MQV8
    Q9VV83 Q9VV83

    Gene LinkOut

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