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    Vm32E Vitelline membrane 32E [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34558, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vm32Eprovided by FlyBase
    Official Full Name
    Vitelline membrane 32Eprovided by FlyBase
    Primary source
    FLYBASE:FBgn0014076
    Locus tag
    Dmel_CG16874
    See related
    AllianceGenome:FB:FBgn0014076
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG16874; Dmel\CG16874; Vm3; VM321; VM32E; Vm32Ea; Vm32Ec; VMP32E
    Summary
    A structural constituent of vitelline membrane. Involved in vitelline membrane formation involved in chorion-containing eggshell formation. Located in egg chorion; extracellular space; and vitelline envelope. Is expressed in follicle cell; main body follicle cell; oocyte associated follicular epithelium; and organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Vm32E in Genome Data Viewer
    Location:
    32E1-32E1; 2-44 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (11171167..11171665, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (11171167..11171665, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Guanylyl cyclase at 32E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ca2+-channel-protein-beta-subunit Neighboring gene Buddy of Hmr 2 Neighboring gene long non-coding RNA:CR43859

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cellular specificity of expression and regulation of Drosophila vitelline membrane protein 32E gene in the follicular epithelium: identification of cis-acting elements. Gargiulo G, et al. Mech Dev, 1991 Nov. PMID 1768620
    2. Regulatory elements in the promoter of the vitelline membrane gene VM32E of Drosophila melanogaster direct gene expression in distinct domains of the follicular epithelium. Cavaliere V, et al. Mol Gen Genet, 1997 Apr 16. PMID 9150256
    3. Spatial activation and repression of the drosophila vitelline membrane gene VM32E are switched by a complex cis-regulatory system. Andrenacci D, et al. Dev Dyn, 2000 Jul. PMID 10878615
    4. Egfr signaling modulates VM32E gene expression during Drosophila oogenesis. Bernardi F, et al. Dev Genes Evol, 2007 Jul. PMID 17569083
    5. Sex-, tissue-, and stage-specific expression of a vitelline membrane protein gene from region 32 of the second chromosome of Drosophila melanogaster. Gigliotti S, et al. Dev Genet, 1989. PMID 2495206

    See all (56) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. heterodimeric complex EcR-B1/Usp mediates the ecdysone-dependent VM32E transcriptional activation in the main body follicle cells.
      Title: EcR-B1 and Usp nuclear hormone receptors regulate expression of the VM32E eggshell gene during Drosophila oogenesis.
    2. the expression of the VM32E gene in the main body follicle cells is modulated by the epidermal growth factor receptor (Egfr) activity
      Title: Egfr signaling modulates VM32E gene expression during Drosophila oogenesis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of vitelline membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in vitelline membrane formation involved in chorion-containing eggshell formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in egg chorion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in vitelline envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vitelline membrane 32E
    Names
    CG16874-PA
    CG16874-PB
    Vm32E-PA
    Vm32E-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      11171167..11171665 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298908.1 → NP_001285837.1  vitelline membrane 32E, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285837.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4UM13, Q24588, Q29QF0, Q629J1, Q9VKI3
      UniProtKB/TrEMBL
      X2J9F7
      Conserved Domains (1) summary
      pfam10542
      Location:37 → 73
      Vitelline_membr; Vitelline membrane cysteine-rich region

    2. NM_057755.2 → NP_477103.1  vitelline membrane 32E, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477103.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4UM13, Q24588, Q29QF0, Q629J1, Q9VKI3
      UniProtKB/TrEMBL
      X2J9F7
      Related
      FBpp0079805, FBtr0080216
      Conserved Domains (1) summary
      pfam10542
      Location:37 → 73
      Vitelline_membr; Vitelline membrane cysteine-rich region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VKI3.1 Q9VKI3
    X2J9F7 X2J9F7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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