mei-38 meiotic 38 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mei-38provided by FlyBase
Official Full Name: meiotic 38provided by FlyBase
Primary source: FLYBASE:FBgn0260986
Locus tag: Dmel_CG14781
See related: AllianceGenome:FB:FBgn0260986
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG14781; d-tpx2; D-TPX2; Dmel\CG14781; EG:80H7.11; Mei-38; rush-3'utr; ssp1; Ssp1
Summary: Enables microtubule binding activity. Involved in meiotic nuclear division and microtubule cytoskeleton organization. Located in kinetochore microtubule and polar microtubule. Colocalizes with mitotic spindle. Is expressed in several structures, including CNS glial cell; central brain primordium; embryonic central brain neurons; ganglia; and larval nervous system. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (1477063..1481420)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (1371096..1372515)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

The Drosophila protein Ssp1/Mei-38 has significant homology to TPX2.
Title: Identification of a TPX2-like microtubule-associated protein in Drosophila.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables microtubule binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in distributive segregation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in distributive segregation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in female meiosis chromosome segregation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in female meiotic nuclear division	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in homologous chromosome segregation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in meiotic spindle organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in microtubule bundle formation	IDA Inferred from Direct Assay more info	PubMed
involved_in mitotic spindle organization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in reciprocal meiotic recombination	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in kinetochore microtubule	IDA Inferred from Direct Assay more info	PubMed
colocalizes_with mitotic spindle	IDA Inferred from Direct Assay more info	PubMed
located_in polar microtubule	IDA Inferred from Direct Assay more info	PubMed
located_in spindle	IDA Inferred from Direct Assay more info	PubMed