U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG4496 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34000, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG4496provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031894
    Locus tag
    Dmel_CG4496
    See related
    AllianceGenome:FB:FBgn0031894
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4496
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in organism and spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG4496 in Genome Data Viewer
    Location:
    27E4-27E4; 2-25 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7185461..7190010, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7185461..7190010, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR46210 Neighboring gene long non-coding RNA:CR44613 Neighboring gene Mitochondrial calcium uptake 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Revisiting the protein-coding gene catalog of Drosophila melanogaster using 12 fly genomes. Lin MF, et al. Genome Res, 2007 Dec. PMID 17989253, Free PMC Article
    2. Genetic modifier screens reveal new components that interact with the Drosophila dystroglycan-dystrophin complex. Kucherenko MM, et al. PLoS One, 2008 Jun 11. PMID 18545683, Free PMC Article
    3. Oviposition behaviour in Drosophila melanogaster: Genetic and behavioural decoupling between oviposition acceptance and preference for natural fruits. Fanara JJ, et al. J Evol Biol, 2023 Jan. PMID 36357966
    4. Genomics of Recombination Rate Variation in Temperature-Evolved Drosophila melanogaster Populations. Winbush A, et al. Genome Biol Evol, 2021 Jan 7. PMID 33247719, Free PMC Article
    5. The genetic architecture of odor-guided behavior in Drosophila melanogaster. Anholt RR, et al. Behav Genet, 2001 Jan. PMID 11529271

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG4496-PA
    CG4496-PB
    CG4496-PC

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7185461..7190010 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135257.1 → NP_609101.1  uncharacterized protein Dmel_CG4496, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609101.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q3ZAM5, Q9VM37
      Related
      FBpp0079047, FBtr0079419
      Conserved Domains (3) summary
      sd00017
      Location:433 → 453
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:245 → 267
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:259 → 282
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001298779.1 → NP_001285708.1  uncharacterized protein Dmel_CG4496, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285708.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q3ZAM5, Q9VM37
      Conserved Domains (3) summary
      sd00017
      Location:433 → 453
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:245 → 267
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:259 → 282
      zf-H2C2_2; Zinc-finger double domain

    3. NM_001298778.1 → NP_001285707.1  uncharacterized protein Dmel_CG4496, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285707.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q3ZAM5, Q9VM37
      Conserved Domains (3) summary
      sd00017
      Location:433 → 453
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:245 → 267
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:259 → 282
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MRU2 Q8MRU2
    Q9VM37 Q9VM37

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools