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    gudu gudu [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34014, updated on 9-Dec-2024

    Summary

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    Official Symbol
    guduprovided by FlyBase
    Official Full Name
    guduprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031905
    Locus tag
    Dmel_CG5155
    See related
    AllianceGenome:FB:FBgn0031905
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG5155; Dmel\CG5155; Gudu
    Summary
    Involved in sperm individualization. Is expressed in adult head; spermatogonium; spermatozoon; and testis. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 23. Orthologous to human ODAD2 (outer dynein arm docking complex subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See gudu in Genome Data Viewer
    Location:
    27F3-27F3; 2-26 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (7388508..7390902)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (7388508..7390902)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene neither inactivation nor afterpotential C Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gudu, an Armadillo repeat-containing protein, is required for spermatogenesis in Drosophila. Cheng W, et al. Gene, 2013 Dec 1. PMID 24055424, Free PMC Article
    2. Organization and regulation of sex-specific thioredoxin encoding genes in the genus Drosophila. Svensson MJ, et al. Dev Genes Evol, 2007 Sep. PMID 17701050
    3. Structure and molecular basis of spermatid elongation in the Drosophila testis. Huang Q, et al. Open Biol, 2023 Nov. PMID 37935354, Free PMC Article
    4. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
    5. Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster. Ni JQ, et al. Nat Methods, 2008 Jan. PMID 18084299, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in sperm individualization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    gudu
    Names
    CG5155-PA
    gudu-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      7388508..7390902
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135267.3 → NP_609111.1  gudu [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609111.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q6NNW8, Q9VM21
      Related
      FBpp0079066
      Conserved Domains (3) summary
      smart00185
      Location:614 → 652
      ARM; Armadillo/beta-catenin-like repeats
      sd00043
      Location:105 → 134
      ARM; armadillo repeat [structural motif]
      cl25709
      Location:214 → 557
      Arm_3; Atypical Arm repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VM21.1 Q9VM21

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