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    CG4911 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39043, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4911provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035959
    Locus tag
    Dmel_CG4911
    See related
    AllianceGenome:FB:FBgn0035959
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4911; FBXO4
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and positive regulation of protein ubiquitination. Predicted to be part of SCF ubiquitin ligase complex. Is expressed in organism. Orthologous to human FBXO33 (F-box protein 33). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4911 in Genome Data Viewer
    Location:
    66F4-66F4; 3-28 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9067195..9072731, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9060295..9065831, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Arginine kinase 2 Neighboring gene Arginine kinase 1 Neighboring gene uncharacterized protein Neighboring gene Tequila

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. graal: a Drosophila gene coding for several mosaic serine proteases. Munier AI, et al. Insect Biochem Mol Biol, 2004 Oct. PMID 15475297
    2. FipoQ/FBXO33, a Cullin-1-based ubiquitin ligase complex component modulates ubiquitination and solubility of polyglutamine disease protein. Chen ZS, et al. J Neurochem, 2019 Jun. PMID 30685895
    3. A conserved F-box gene with unusual transcript localization. Das T, et al. Dev Genes Evol, 2002 Apr. PMID 11976951
    4. The T-box-encoding Dorsocross genes function in amnioserosa development and the patterning of the dorsolateral germ band downstream of Dpp. Reim I, et al. Development, 2003 Jul. PMID 12783790
    5. F-box proteins: the key to protein degradation. Ho MS, et al. J Biomed Sci, 2006 Mar. PMID 16463014

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISM
    Inferred from Sequence Model
    more info
    		  
    involved_in positive regulation of protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4911-PA
    CG4911-PB
    CG4911-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9067195..9072731 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300061.1 → NP_001286990.1  uncharacterized protein Dmel_CG4911, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286990.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VST7
      Conserved Domains (1) summary
      pfam00646
      Location:8 → 53
      F-box; F-box domain

    2. NM_001274684.1 → NP_001261613.1  uncharacterized protein Dmel_CG4911, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261613.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PEL5
      Conserved Domains (1) summary
      pfam00646
      Location:8 → 53
      F-box; F-box domain

    3. NM_140028.2 → NP_648285.1  uncharacterized protein Dmel_CG4911, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648285.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VST7
      Related
      FBpp0076269
      Conserved Domains (1) summary
      pfam00646
      Location:8 → 53
      F-box; F-box domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PEL5 M9PEL5
    Q95RW0 Q95RW0
    Q9VST7 Q9VST7

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