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    emei emei [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39250, updated on 17-Dec-2024

    Summary

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    Official Symbol
    emeiprovided by FlyBase
    Official Full Name
    emeiprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036133
    Locus tag
    Dmel_CG7638
    See related
    AllianceGenome:FB:FBgn0036133
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7638; Dmel\CG7638
    Summary
    Involved in positive regulation of endoplasmic reticulum calcium ion concentration. Located in endoplasmic reticulum. Is expressed in several structures, including gut section; head epidermis primordium; larval muscle cell; mesoderm; and visceral mesoderm derivative. Orthologous to human TMEM161A (transmembrane protein 161A) and TMEM161B (transmembrane protein 161B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See emei in Genome Data Viewer
    Location:
    68A7-68A7; 3-34 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (11109690..11112117)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (11102790..11105217)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Superoxide dismutase 1 Neighboring gene Forkhead box K

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A novel regulator of ER Ca(2+) drives Hippo-mediated tumorigenesis. Ma X, et al. Oncogene, 2020 Feb. PMID 31649333
    2. The MOF chromobarrel domain controls genome-wide H4K16 acetylation and spreading of the MSL complex. Conrad T, et al. Dev Cell, 2012 Mar 13. PMID 22421046
    3. Glial TGFβ activity promotes neuron survival in peripheral nerves. Lassetter AP, et al. J Cell Biol, 2023 Jan 2. PMID 36399182, Free PMC Article
    4. Laser microdissection of sensory organ precursor cells of Drosophila microchaetes. Buffin E, et al. PLoS One, 2010 Feb 19. PMID 20174573, Free PMC Article
    5. A genetic interaction map of cell cycle regulators. Billmann M, et al. Mol Biol Cell, 2016 Apr 15. PMID 26912791, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in positive regulation of endoplasmic reticulum calcium ion concentration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    emei
    Names
    CG7638-PA
    emei-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      11109690..11112117
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140182.3 → NP_648439.1  emei [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648439.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VTF5
      Related
      FBpp0075940
      Conserved Domains (1) summary
      pfam10268
      Location:2 → 493
      Tmemb_161AB; Predicted transmembrane protein 161AB
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VTF5 Q9VTF5

    Gene LinkOut

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